The last decade has seen an enormous expansion in the genetic toolbox of model
organisms. This has been particularly apparent in the fruitfly, Drosophila melanogaster, in …

Understanding the principles of information processing in neural circuits requires systematic
characterization of the participating cell types and their connections, and the ability to …

The Hippo signaling pathway is widely considered a master regulator of organ growth
because of the prominent overgrowth phenotypes caused by experimental manipulation of …

Many animals keep track of their angular heading over time while navigating through their
environment. However, a neural-circuit architecture for computing heading has not been …

We generated a library of~ 1000 Drosophila stocks in which we inserted a construct in the
intron of genes allowing expression of GAL4 under control of endogenous promoters while …

We describe a new repressible binary expression system based on the regulatory genes
from the Neurospora qa gene cluster. This" Q system" offers attractive features for transgene …

Summary Background: Olfactory receptor neurons (ORNs) convey chemical information into
the brain, producing internal representations of odors detected in the periphery. A …

Research in the fruit fly Drosophila melanogaster has led to insights in neural development,
axon guidance, ion channel function, synaptic transmission, learning and memory, diurnal …

The development of two-component expression systems in Drosophila melanogaster, one of
the most powerful genetic models, has allowed the precise manipulation of gene function in …

The mushroom body (MB) of the insect brain has important roles in odor learning and
memory and in diverse other brain functions. To elucidate the anatomical basis underlying …