Selenium (Se) is an essential micronutrient of organism and has important function. It
participates in the functions of selenoprotein in several manners. In recent years, Se has …

Chagas disease is one of the most prevalent tropical neglected diseases and causes high
mortality and morbidity in endemic countries. Current treatments for this disease, nifurtimox …

The selenium element is essential to some life forms and its biological-chemistry function is
mainly performed by the selenol/selenolate moiety (–SeH/–Se–) in a few selenoproteins …

We modified the thiazolidinic ring at positions N3, C4, and C5, yielding compounds 6–24.
Compounds with a phenyl at position N3, 15–19, 22–24, exhibited better inhibitory …

Herein, we report the preparation of a panel of Schiff bases analogues as antiprotozoal
agents by modification of the stereoelectronic effects of the substituents on N-1 and N-4 and …

Human American trypanosomiasis, commonly called Chagas disease, is one of the most
neglected illnesses in the world and remains one of the most prevalent chronic infectious …

Chagas disease is a tropical infection caused by the protozoan parasite Trypanosoma cruzi
and a global public health concern. It is a paradigmatic example of a chronic disease without …

Chagas disease is an infection caused by protozoan Trypanosoma cruzi, which affects
approximately 8–10 million people worldwide. Benznidazole is the only drug approved for …

New square-planar Pd (II) and Pt (II) complexes with 8-quinolinecarboxaldehyde
selenosemicarbazone have been synthesized and characterized by use of elemental …

Current treatment for Chagas disease is based on only two drugs: benznidazole and
nifurtimox. Compounds containing sulfur (S) in their structure have shown promising results …