MicroRNAs in cardiac hypertrophy

N Wehbe, SA Nasser, G Pintus, A Badran… - International journal of …, 2019 - mdpi.com
Like other organs, the heart undergoes normal adaptive remodeling, such as cardiac
hypertrophy, with age. This remodeling, however, is intensified under stress and …

The Role of TGF‐β Signaling Pathways in Cancer and Its Potential as a Therapeutic Target

Y Yang, WL Ye, RN Zhang, XS He… - Evidence‐Based …, 2021 - Wiley Online Library
The transforming growth factor‐β (TGF‐β) signaling pathway mediates various biological
functions, and its dysregulation is closely related to the occurrence of malignant tumors …

Ionone is more than a violet's fragrance: A review

L Aloum, E Alefishat, A Adem, G Petroianu - Molecules, 2020 - mdpi.com
The term ionone is derived from “iona”(Greek for violet) which refers to the violet scent and
“ketone” due to its structure. Ionones can either be chemically synthesized or endogenously …

TET2 protects against vascular smooth muscle cell apoptosis and intimal thickening in transplant vasculopathy

AC Ostriker, Y Xie, R Chakraborty, AJ Sizer, Y Bai… - Circulation, 2021 - Am Heart Assoc
Background: Coronary allograft vasculopathy (CAV) is a devastating sequela of heart
transplant in which arterial intimal thickening limits coronary blood flow. There are currently …

Cationic nanoplastic causes mitochondrial dysfunction in neural progenitor cells and impairs hippocampal neurogenesis

S Yang, S Lee, Y Lee, JH Cho, SH Kim, ES Ha… - Free Radical Biology …, 2023 - Elsevier
Nanoplastics (NPs) exposure to humans can occur through various routes, including the
food chain, drinking water, skin contact, and respiration. NPs are plastics with a diameter of …

Sorting nexins in protein homeostasis

SE Hanley, KF Cooper - Cells, 2020 - mdpi.com
Protein homeostasis is maintained by removing misfolded, damaged, or excess proteins and
damaged organelles from the cell by three major pathways; the ubiquitin-proteasome …

[HTML][HTML] Daidzein synergizes with gefitinib to induce ROS/JNK/c-Jun activation and inhibit EGFR-STAT/AKT/ERK pathways to enhance lung adenocarcinoma cells …

TG Mhone, MC Chen, CH Kuo, TC Shih… - … Journal of Biological …, 2022 - ncbi.nlm.nih.gov
Lung cancer is the major cause of cancer associated mortality. Mutations in EGFR have
been implicated in lung cancer pathogenesis. Gefitinib (GF) is a RTKI (receptor tyrosine …

Cordyceps cicadae polysaccharides inhibit human cervical cancer hela cells proliferation via apoptosis and cell cycle arrest

J Xu, ZC Tan, ZY Shen, XJ Shen, SM Tang - Food and Chemical Toxicology, 2021 - Elsevier
The present study presented the extraction and purification of polysaccharides from
artificially cultured Cordyceps cicadae and wild Cordyceps cicadae by pre-soaking …

A comprehensive review of the impact of chromium picolinate on testicular steroidogenesis and antioxidant balance

R Moreira, AD Martins, MG Alves… - Antioxidants, 2023 - mdpi.com
Low testosterone (T) levels are a major cause of male infertility, as this hormone is crucial for
several processes throughout the entire male reproductive tract. Leydig cells (LC) produce T …

CDK regulators—Cell cycle progression or apoptosis—Scenarios in normal cells and cancerous cells

M D'costa, A Bothe, S Das, SU Kumar… - Advances in Protein …, 2023 - Elsevier
Serine/threonine kinases called cyclin-dependent kinases (CDKs) interact with cyclins and
CDK inhibitors (CKIs) to control the catalytic activity. CDKs are essential controllers of RNA …