Epigenetic mechanisms, which include DNA methylation, histone modification, and
microRNA (miRNA), can produce heritable phenotypic changes without a change in DNA …

Research on psoriasis pathogenesis has largely increased knowledge on skin biology in
general. In the past 15 years, breakthroughs in the understanding of the pathogenesis of …

Psoriasis is a common inflammatory skin disease involving interactions between
keratinocytes and immune cells that significantly affects the quality of life. It is characterized …

Psoriasis is a chronic, systemic, immune-mediated disease with an incidence of
approximately 2%. The pathogenesis of the disease is complex and not yet fully understood …

Psoriasis is a common, chronic, and inflammatory skin disease with a high burden on
individuals, health systems, and society worldwide. With the immunological pathologies and …

Psoriasis vulgaris is a chronic, immune-mediated, inflammatory, polygenic skin disorder
affecting approximately 2% of the population. It has a great impact on quality of life; patients …

Neuroinflammation is a major contributor to secondary neuronal injury that accounts for a
significant proportion of final brain cell loss in neonatal hypoxic-ischemic encephalopathy …

Exosomes are nano-sized cargos with a lipid bilayer structure carrying diverse biomolecules
including lipids, proteins, and nucleic acids. These small vesicles are secreted by most types …

Oxygen availability varies throughout the human body in health and disease. Under
physiological conditions, oxygen availability drops from the lungs over the blood stream …

Keratinocyte differentiation is an essential process for epidermal stratification and stratum
corneum formation. Keratinocytes proliferate in the basal layer of the epidermis and start …