Penetration through the skin barrier

JB Nielsen, E Benfeldt, R Holmgaard - Skin Barrier Function, 2016 - karger.com
The skin is a strong and flexible organ with barrier properties essential for maintaining
homeostasis and thereby human life. Characterizing this barrier is the ability to prevent …

Transitioning from Pickering emulsions to Pickering emulsion hydrogels: A potential advancement in cosmeceuticals

A Rajoo, SP Siva, CS Sia, ES Chan, BT Tey… - European Journal of …, 2024 - Elsevier
Cosmeceuticals, focusing on enhancing skin health and appearance, heavily rely on
emulsions as one of the common mediums. These emulsions pose a challenge due to their …

Impact of physiologically relevant temperatures on dermal absorption of active substances-an ex-vivo study in human skin

S Kilo, J Wick, SM Vijayan, T Göen, RE Horch… - Toxicology in Vitro, 2020 - Elsevier
Skin temperature plays a certain role in the dermal absorption of substances, but the extent
and mechanisms of skin temperatures-induced modulation in ranges caused by …

Biology of percutaneous penetration

NR Blickenstaff, G Coman, CM Blattner… - Reviews on …, 2014 - degruyter.com
Background: Percutaneous penetration is a passive process that can occur following skin
exposure to chemicals used in agriculture, industry, pharmaceuticals, cosmetics, and in the …

Protoporphyrin IX formation after topical application of methyl aminolaevulinate and BF‐200 aminolaevulinic acid declines with age

CV Nissen, PA Philipsen, HC Wulf - British Journal of …, 2015 - academic.oup.com
Background Topical photodynamic therapy (PDT) is a popular treatment modality in
dermatology. The effect of PDT in epidermal cells depends on formation of protoporphyrin IX …

Effectiveness of topical sodium thiosulfate for ectopic calcifications and ossifications. Results of the CATSS-O study

A Gauffenic, V Ratsimbazafy, A Ostertag… - Seminars in Arthritis and …, 2023 - Elsevier
INTRODUCTION Ectopic calcifications (ECs) and heterotopic ossifications (HOs) form in non-
mineralized tissues, most often in subcutaneous and muscular areas. Local and systemic …

Regulatory development of geriatric medicines: to GIP or not to GIP?

B De Spiegeleer, E Wynendaele, N Bracke… - Ageing Research …, 2016 - Elsevier
Geriatric patients represent the main users of medicines, but are historically often minimally
included in clinical trials, resulting in a gap in the knowledge of the benefit/risk balance of …

Calcium, magnesium and aluminium ions as decontaminating agents against dermal fluoride absorption following hydrofluoric acid exposure

SM Vijayan, T Göen, K Dennerlein, RE Horch… - Toxicology In Vitro, 2021 - Elsevier
The fluoride ions of the industrially largely irreplaceable, locally corrosive hydrofluoric acid
(HF) can scavenge cations in biological tissues, which explains their high toxic potential …

[PDF][PDF] Transfersomal nanoparticles of keratolytic and antibacterial agents for enhanced transdermal delivery

AAH Abdellatif, HA Abou-Taleb - … of Nanotechnology & …, 2016 - naturalspublishing.com
The aim of this study was to prepare transfersomal formulations as transdermal deliveries for
drugs of bad solubility. Transfersomes (TRSs) were chosen and prepared containing sulfur …

Optimization of photodynamic therapy using negative pressure

PFC Menezes, MB Requena… - Photomedicine and laser …, 2014 - liebertpub.com
Objective: The goal of this study is to demonstrate an alternative procedure to perform
topical photodynamic therapy (PDT). Here, we propose the combined use of negative …