DRAMP 2.0, an updated data repository of antimicrobial peptides

X Kang, F Dong, C Shi, S Liu, J Sun, J Chen, H Li, H Xu… - Scientific data, 2019 - nature.com
Abstract Data Repository of Antimicrobial Peptides (DRAMP, http://dramp. cpu-bioinfor. org/)
is an open-access comprehensive database containing general, patent and clinical …

Bioprospection of actinobacteria derived from freshwater sediments for their potential to produce antimicrobial compounds

Zothanpuia, AK Passari, VV Leo, P Chandra… - Microbial cell …, 2018 - Springer
Background Actinobacteria from freshwater habitats have been explored less than from
other habitats in the search for compounds of pharmaceutical value. This study highlighted …

Variants of self-assembling peptide, KLD-12 that show both rapid fracture healing and antimicrobial properties

JK Tripathi, S Pal, B Awasthi, A Kumar, A Tandon… - Biomaterials, 2015 - Elsevier
Abstract KLD-12 (KLD) is a 12-residue self-assembling peptide that can adopt nano-
structures and is known for its tissue-engineering properties. Our objective was to introduce …

Quantum Dot–Peptide–Fullerene Bioconjugates for Visualization of in Vitro and in Vivo Cellular Membrane Potential

OK Nag, MH Stewart, JR Deschamps, K Susumu… - ACS …, 2017 - ACS Publications
We report the development of a quantum dot (QD)–peptide–fullerene (C60) electron transfer
(ET)-based nanobioconjugate for the visualization of membrane potential in living cells. The …

Dual antimicrobial and anticancer activity of a novel synthetic α-helical antimicrobial peptide

B Thankappan, J Sivakumar, S Asokan… - European Journal of …, 2021 - Elsevier
Antimicrobial peptides (AMPs) are increasingly sought-after and researched antimicrobial
agents due to its desired pharmacological properties and the continuous diminishing …

Selective phenylalanine to proline substitution for improved antimicrobial and anticancer activities of peptides designed on phenylalanine heptad repeat

AK Tripathi, T Kumari, A Tandon, M Sayeed, T Afshan… - Acta biomaterialia, 2017 - Elsevier
Introducing cell-selectivity in antimicrobial peptides (AMPs) without compromising the
antimicrobial and anti-endotoxin properties is a crucial step towards the development of new …

Natural and redesigned wasp venom peptides with selective antitumoral activity

MDT Torres, GP Andrade, RH Sato… - Beilstein Journal of …, 2018 - beilstein-journals.org
About 1 in 8 US women (≈ 12%) will develop invasive breast cancer over the course of their
lifetime. Surgery, chemotherapy, radiotherapy, and hormone manipulation constitute the …

[HTML][HTML] New antimicrobial peptide kills drug-resistant pathogens without detectable resistance

JK Lee, T Luchian, Y Park - Oncotarget, 2018 - ncbi.nlm.nih.gov
Clavaspirin peptide (CSP) is derived from the pharyngeal tissues of the tunicate Styela
clava. The 23-amino acid peptide is histidine-rich and amidated at the N-terminus. CSP …

[HTML][HTML] A review emphasizing on utility of heptad repeat sequence as a tool to design pharmacologically safe peptide-based antibiotics

V Yadav, R Misra - Biochimie, 2021 - Elsevier
Extensive usage of antibiotics has created an unprecedented scenario of the rapid
emergence of many drug-resistant bacteria, which has become an alarming public health …

Self-assembling nano-globular peptide from human lactoferrin acts as a systemic enhancer of bone regeneration: A novel peptide for orthopedic application

S Pal, M Sayeed, A Kumar, DP Verma… - … Applied Materials & …, 2021 - ACS Publications
A technology for systemic and repeated administration of osteogenic factors for orthopedic
use is an unmet medical need. Lactoferrin (∼ 80 kDa), present in milk, is known to support …