In an elegant example of bench-to-bedside research, a hypothesis that cells in the outflow
pathway actively regulate conventional outflow resistance was proposed in the 1990s and …

Retinal ganglion cells, the neurons that die in glaucoma, are endowed with a high
metabolism requiring optimal provision of oxygen and nutrients to sustain their activity. The …

Normal tension glaucoma (NTG) has remained a challenging disease. We review, from an
epidemiological perspective, why we should redefine normality, act earlier at lower pre …

Glaucoma is a neurodegenerative disease of the visual system and leading cause of
blindness worldwide. The disease is associated with sensitivity to intraocular pressure (IOP) …

Alterations in ocular blood flow have been implicated in mechanisms that lead to vision loss
in patients with various ocular disorders such as diabetic retinopathy, glaucoma, and age …

Neurovascular coupling, also termed functional hyperemia, is one of the physiological key
mechanisms to adjust blood flow in a neural tissue in response to functional activity. In the …

Glaucoma is a leading cause of blindness worldwide. Normal-tension glaucoma (NTG) is a
type of open-angle glaucoma with intraocular pressure measurements always 21 mm Hg or …

With a growing elderly population in the European Union, age-related diseases associated
with unhealthy aging pose increasing public health challenges, including a loss of …

Non-arteritic anterior ischemic optic neuropathy (NA-AION) represents one of the most
important causes of blindness or severely impaired vision in middle-aged and elderly …

Primary open-angle glaucoma (POAG) has been suggested to be a neurodegenerative
disease associated with altered cerebral vascular hemodynamics and widespread …