Beneficial and detrimental aspects of miRNAs as chief players in breast cancer: a comprehensive review

A Ismail, HA El-Mahdy, AI Abulsoud… - International Journal of …, 2023 - Elsevier
Breast cancer (BC) is the most common cancer in women and poses a serious threat to their
health. Despite familiarity with factors affecting its etiology, initiation, progression, treatment …

Signaling pathways modulated by miRNAs in breast cancer angiogenesis and new therapeutics

BM Hussen, A Salihi, ST Abdullah, MF Rasul… - … -Research and Practice, 2022 - Elsevier
MicroRNAs (miRNAs) act as oncogenes or tumor suppressors by suppressing the
expression of target genes, some of which are engaged in angiogenic signaling pathways …

Potential utility of miRNAs for liquid biopsy in breast cancer

X Liu, D Papukashvili, Z Wang, Y Liu, X Chen… - Frontiers in …, 2022 - frontiersin.org
Breast cancer (BC) remains the most prevalent malignancy due to its incidence rate,
recurrence, and metastasis in women. Conventional strategies of cancer detection …

MicroRNA dysregulation in early breast cancer diagnosis: A systematic review and meta-analysis

A Garrido-Palacios, AM Rojas Carvajal… - International Journal of …, 2023 - mdpi.com
Breast cancer continues to be the leading cause of death in women worldwide.
Mammography, which is the current gold standard technique used to diagnose it, presents …

The emerging role of miR-20b in human cancer and other disorders: Pathophysiology and therapeutic implications

S Khalilian, H Abedinlou, BM Hussen… - Frontiers in …, 2022 - frontiersin.org
miR-20b is a microRNA with diverse and somehow contradictory roles in the pathogenesis
of human disorders, especially cancers. It has been known to be a tumor suppressor in …

Extracellular Vesicles' Role in Angiogenesis and Altering Angiogenic Signaling

M Ateeq, M Broadwin, FW Sellke, MR Abid - Medical Sciences, 2024 - mdpi.com
Angiogenesis, the process of new blood vessels formation from existing vasculature, plays a
vital role in development, wound healing, and various pathophysiological conditions. In …

MiR-18a-5p attenuates HER2-positive breast cancer development by regulating PI3K/AKT pathway

Y Liu, H Yang - Cancer Biology & Therapy, 2023 - Taylor & Francis
Objective: Human epidermal growth factor receptor 2 positive (HER2+) breast cancer (BC) is
associated with poor prognosis. This study aimed to elucidate the role of miR− 18a− 5p in …

[HTML][HTML] New insights of miRNA molecular mechanisms in breast cancer brain metastasis and therapeutic targets

BM Hussen, KH Abdullah, SR Abdullah… - Non-coding RNA …, 2023 - Elsevier
Brain metastases in breast cancer (BC) patients are often associated with a poor prognosis.
Recent studies have uncovered the critical roles of miRNAs in the initiation and progression …

Regulation of Inflammasome by microRNAs in Triple-Negative Breast Cancer: New Opportunities for Therapy

S Dinescu, M Costache - International journal of molecular sciences, 2023 - mdpi.com
During the past decade, researchers have investigated the molecular mechanisms of breast
cancer initiation and progression, especially triple-negative breast cancer (TNBC), in order …

[HTML][HTML] A review on the role of ncRNAs in the pathogenesis of cholangiocarcinoma

S Ghafouri-Fard, A Safarzadeh, BM Hussen… - International Journal of …, 2023 - Elsevier
Cholangiocarcinoma is a rare tumor but a challenging cancer in terms of pathological
changes, clinical manifestations and therapeutic options. Recent studies have provided …