A woman receives a diagnosis of diffuse large B-cell lymphoma; a standard chemotherapy regimen is recommended. Use of prophylactic granulocyte CSF is considered. G-CSF …
J Klastersky, J De Naurois, K Rolston… - Annals of …, 2016 - annalsofoncology.org
Despite major advances in prevention and treatment, FN remains one of the most frequent and serious complications of cancer chemotherapy (ChT). It is a major cause of morbidity …
J Klastersky, M Paesmans - Supportive care in cancer, 2013 - Springer
Abstract The Multinational Association for Supportive Care in Cancer risk index score developed, through a multinational collaboration, was published in 2000 with the aim to …
M Aapro, R Boccia, R Leonard, C Camps… - Supportive Care in …, 2017 - Springer
Purpose Chemotherapy-induced febrile neutropenia (FN) causes treatment delays and interruptions and can have fatal consequences. Current guidelines provide …
DC Dale, J Crawford, Z Klippel, M Reiner… - Supportive Care in …, 2018 - Springer
Abstract Purpose Filgrastim (NEUPOGEN®) is the originator recombinant human granulocyte colony-stimulating factor widely used for preventing neutropenia-related …
K Blackwell, V Semiglazov, D Krasnozhon… - Annals of …, 2015 - Elsevier
Background Biosimilars of filgrastim are in widespread clinical use in Europe. This phase III study compares biosimilar filgrastim (EP2006), with the US-licensed reference product …
L Koenderman, K Tesselaar, N Vrisekoop - Trends in immunology, 2022 - cell.com
The half-life of human neutrophils is still controversial, with estimates ranging from 7–9 h to 3.75 days. This debate should be settled to understand neutrophil production in the bone …
T Arvedson, J O'Kelly, BB Yang - BioDrugs, 2015 - Springer
Filgrastim, a recombinant methionyl human granulocyte colony-stimulating factor (G-CSF)(r- metHuG-CSF), is efficacious in stimulating neutrophil production and maturation to prevent …
AM Pfeil, K Allcott, R Pettengell, G von Minckwitz… - Supportive care in …, 2015 - Springer
Purpose Pegfilgrastim was introduced over a decade ago. Other long-acting granulocyte colony-stimulating factors (G-CSFs) have recently been developed. We systematically …