Doxorubicin is a chemotherapeutic drug used for the treatment of various malignancies;
however, patients can experience cardiotoxic effects and this has limited the use of this …

Modern cancer therapy has successfully cured many cancers and converted a terminal
illness into a chronic disease. Because cancer patients often have coexisting heart …

ESC Guidelines e341 (1) the specific situation of the patient. In this respect, it is specified
that, unless otherwise provided for by national regulations, offlabel use of medication should …

Since the 1960s, paediatric oncologists have gradually become better organised in large
study groups and participation in clinical trials is today considered as the standard of care …

Genome-wide association studies (GWAS) provide an agnostic approach for investigating
the genetic basis of complex diseases. In oncology, GWAS of nearly all common …

Survivors of childhood, adolescent, and young adult cancer, previously treated with
anthracycline chemotherapy (including mitoxantrone) or radiotherapy in which the heart was …

Through the success of basic and disease-specific research, cancer survivors are one of the
largest growing subsets of individuals accessing the healthcare system. Interestingly …

Cardiovascular disease (CVD), which includes cardiomyopathy/heart failure, coronary artery
disease, stroke, pericardial disease, arrhythmias, and valvular and vascular dysfunction, is a …

In the field of cardio-oncology, it is well recognised that despite the benefits of chemotherapy
in treating and possibly curing cancer, it can cause catastrophic damage to bystander …

Background: Multiple pharmacogenomic studies have identified the synonymous genomic
variant rs7853758 (G> A, L461L) and the intronic variant rs885004 in SLC28A3 (solute …