Motor symptoms in Parkinson's disease: A unified framework

AA Moustafa, S Chakravarthy, JR Phillips… - Neuroscience & …, 2016 - Elsevier
Parkinson's disease (PD) is characterized by a range of motor symptoms. Besides the
cardinal symptoms (akinesia and bradykinesia, tremor and rigidity), PD patients show …

Evolving concepts on bradykinesia

M Bologna, G Paparella, A Fasano, M Hallett… - Brain, 2020 - academic.oup.com
Bradykinesia is one of the cardinal motor symptoms of Parkinson's disease and other
parkinsonisms. The various clinical aspects related to bradykinesia and the …

The benefits and mechanisms of exercise training for Parkinson's disease

YS Feng, SD Yang, ZX Tan, MM Wang, Y Xing, F Dong… - Life sciences, 2020 - Elsevier
Parkinson's disease (PD) is a significantly progressive neurodegenerative disease
characterised by both motor and nonmotor disorders. The main pathological characteristics …

Characterizing mild cognitive impairment in incident Parkinson disease: the ICICLE-PD study

AJ Yarnall, DP Breen, GW Duncan, TK Khoo… - Neurology, 2014 - AAN Enterprises
Objective: To describe the frequency of mild cognitive impairment (MCI) in Parkinson
disease (PD) in a cohort of newly diagnosed incident PD cases and the associations with a …

Cognitive performance and neuropsychiatric symptoms in early, untreated Parkinson's disease

D Weintraub, T Simuni, C Caspell‐Garcia… - Movement …, 2015 - Wiley Online Library
This study was undertaken to determine the prevalence and correlates of cognitive
impairment (CI) and neuropsychiatric symptoms (NPS) in early, untreated patients with …

Natural course of mild cognitive impairment in Parkinson disease: a 5-year population-based study

KF Pedersen, JP Larsen, OB Tysnes, G Alves - Neurology, 2017 - AAN Enterprises
Objective: To examine the incidence, progression, and reversion of mild cognitive
impairment in patients with Parkinson disease (PD-MCI) over 5 years. Methods: A …

Altered cholinergic innervation in de novo Parkinson's disease with and without cognitive impairment

S van der Zee, P Kanel, MJJ Gerritsen… - Movement …, 2022 - Wiley Online Library
Background Altered cholinergic innervation plays a putative role in cognitive impairment in
Parkinson's disease (PD) at least in advanced stages. Identification of the relationship …

Evolution of mild cognitive impairment in Parkinson disease

M Broeders, RMA De Bie, DC Velseboer… - Neurology, 2013 - AAN Enterprises
Objective: We examined the development of Parkinson disease (PD)–mild cognitive
impairment (MCI) in patients with newly diagnosed PD over 5 years using recently proposed …

Mild cognitive impairment in newly diagnosed Parkinson's disease: a longitudinal prospective study

G Santangelo, C Vitale, M Picillo, M Moccia… - Parkinsonism & Related …, 2015 - Elsevier
Abstract Introduction In PD, Mild Cognitive Impairment (PD-MCI) occurs since early stages of
disease. The aims were to assess presence of PD-MCI in untreated, drug-naive PD patients …

Cognitive impairment in early‐stage non‐demented Parkinson's disease patients

HCV Pfeiffer, A Løkkegaard… - Acta Neurologica …, 2014 - Wiley Online Library
Objectives In Parkinson's disease (PD), Parkinson's disease dementia (PDD) and
Parkinson's disease–mild cognitive impairment (PD‐MCI) are common. PD‐MCI is a risk …