Leishmania parasites are the organisms responsible for one of the most important tropical
diseases, leishmaniasis. This neglected disease mainly affects populations in developing or …

Topical drug delivery is preferable route over systemic delivery in case of Cutaneous
leishmaniasis (CL). Among the available agents, amphotericin B (AmB) and pentamidine …

Migraine is a progressive neurological condition often accompanied by nausea and
vomiting. Various drugs have recently been used in the treatment of migraine, including …

Objectives Rivaroxaban (RXB), a novel Xa inhibitor having groundbreaking therapeutic
potential. However, this drug is associated with few limitations, including its …

The growing need for innovative drug delivery systems has led to extensive research to
address the limitations associated with conventional dosage forms. Lipid nanoparticles have …

Purpose Anti-leishmanial medications administered by oral and parenteral routes are less
effective for treatment of cutaneous leishmaniasis (CL) and cause toxicity, hence targeted …

Tacrolimus (TRL) is used for the treatment of atopic dermatitis (AD) due to its T-cell
stimulation effect. However, its significantly poor water solubility, low penetration and …

Leishmaniasis, an endemic tropical ailment, has invariably been categorized as one of the
“neglected tropical diseases” and is constantly linked with poverty. However, under current …

Transethosomes, classified as 3rd generation nanocarriers, have gained global acclaim due
to their profound potential in addressing diverse medical conditions. Their superior dermal …

Résumé La leishmaniose est la maladie parasitaire la plus mortelle après le paludisme et il
n'existe pas de vaccin chez l'homme. Des traitements sont actuellement disponibles, mais ils …