Tests for serum transglutaminase and endomysial antibodies do not detect most patients with celiac disease and persistent villous atrophy on gluten-free diets: a meta …

JA Silvester, S Kurada, A Szwajcer, CP Kelly… - Gastroenterology, 2017 - Elsevier
Background & Aims Tests to measure serum endomysial antibodies (EMA) and antibodies to
tissue transglutaminase (tTG) were developed to screen for celiac disease in patients …

Update on serologic testing in celiac disease

DA Leffler, D Schuppan - Official journal of the American College …, 2010 - journals.lww.com
Contemporary serologic testing has revolutionized the field of celiac disease (CD). Highly
accurate serologic assays have shown the prevalence of CD to be nearly 1: 100 in many …

The gut barrier: new acquisitions and therapeutic approaches

F Scaldaferri, M Pizzoferrato, V Gerardi… - Journal of clinical …, 2012 - journals.lww.com
The intestinal barrier serves 2 critical functions for the survival of the individual: first, it allows
nutrient absorption and second, it defends the body from dangerous macromolecule …

Systematic review: the evidence base for long‐term management of coeliac disease

ML Haines, RP Anderson… - Alimentary pharmacology …, 2008 - Wiley Online Library
Background While gluten‐free diet is an effective treatment for coeliac disease, the need for
and goals of long‐term management of patients are poorly defined. Aim To review …

The role of innate signaling in the homeostasis of tolerance and immunity in the intestine

JM Wells, LMP Loonen, JM Karczewski - International Journal of Medical …, 2010 - Elsevier
In the intestine innate recognition of microbes is achieved through pattern recognition
receptor (PRR) families expressed in immune cells and different cell lineages of the …

Fecal calprotectin concentration in celiac disease

V Ertekin, MA Selimoglu, A Turgut… - Journal of clinical …, 2010 - journals.lww.com
Background As FC is regarded as a marker of inflammation in the gastrointestinal tract, we
hypothesized that it might be increased in untreated CD. Study The study included 29 newly …

Safety of oats in children with celiac disease: a double-blind, randomized, placebo-controlled trial

E Lionetti, S Gatti, T Galeazzi, N Caporelli… - The Journal of …, 2018 - Elsevier
Objective To evaluate the long-term validity and safety of pure oats in the treatment of
children with celiac disease. Study design This noninferiority clinical trial used a double …

Non‐celiac gluten sensitivity: How its gut immune activation and potential dietary management differ from celiac disease

V Rotondi Aufiero, A Fasano… - Molecular nutrition & …, 2018 - Wiley Online Library
Non‐celiac gluten sensitivity (NCGS) is a clinical entity triggered by the ingestion of gluten‐
containing grains leading to intestinal and/or extraintestinal symptoms that resolve once the …

The measurement and clinical significance of intestinal permeability

CW Teshima, JB Meddings - Current gastroenterology reports, 2008 - Springer
This article discusses the concept of intestinal permeability and the barrier function of the
gut, elaborates on tight junction structure and the dynamic nature of its composition, outlines …

Protease‐activated receptor 2 and gut permeability: a review

L Bueno, J Fioramonti - Neurogastroenterology & Motility, 2008 - Wiley Online Library
Digestive tract proteases are best known for their proteolytic activity in the digestion of
alimentary proteins. However, during the last decade, a possible role of proteases as …