Insights into potential targets for therapeutic intervention in epilepsy

C Zavala-Tecuapetla, M Cuellar-Herrera… - International journal of …, 2020 - mdpi.com
Epilepsy is a chronic brain disease that affects approximately 65 million people worldwide.
However, despite the continuous development of antiepileptic drugs, over 30% patients with …

The role of melatonin and its analogues in epilepsy

S Khan, M Khurana, P Vyas, D Vohora - Reviews in the …, 2021 - degruyter.com
Extensive research has gone into proposing a promising link between melatonin
administration and attenuation of epileptic activity, the majority of which suggest its …

Ryanodine receptors drive neuronal loss and regulate synaptic proteins during epileptogenesis

PX Royero, GSV Higa, DS Kostecki… - Experimental …, 2020 - Elsevier
Status epilepticus (SE) is a clinical emergency that can lead to the development of temporal
lobe epilepsy (TLE). The development and maintenance of spontaneous seizures in TLE are …

Ameliorating impacts of ginseng on the apoptosis of spermatogenic cells and sperm quality in temporal lobe epilepsy rat model treated with valproate

M Ganjkhani, S Nourozi, R Bigonah, A Rostami… - Andrologia, 2019 - Wiley Online Library
Both epilepsy and valproate (VPA), as an antiepileptic drug, negatively affect male sexual
function. The present study was conducted to evaluate the ameliorating impacts of ginseng …

Dynamic effects of miR-20a-5p on hippocampal ripple energy after status epilepticus in rats

X Zhang, Y Yi, L Cheng, H Chen, Y Hu - Experimental Brain Research, 2023 - Springer
To determine the dynamic effects of miR-20a-5p on hippocampal ripple energy in rats after
status epilepticus (SE). A lithium pilocarpine (LiCl-PILO)-induced rat model of status …

Dynamic changes in spectral and spatial signatures of high frequency oscillations in rat hippocampi during epileptogenesis in acute and chronic stages

PP Song, J Xiang, L Jiang, HS Chen, BK Liu… - Frontiers in …, 2016 - frontiersin.org
Objective To analyze spectral and spatial signatures of high frequency oscillations (HFOs),
which include ripples and fast ripples (FRs,> 200 Hz) by quantitatively assessing average …

[HTML][HTML] Screening of potential biomarkers in propofol-induced neurotoxicity via bioinformatics prediction and experimental verification

T He, J Huang, B Peng, M Wang, Q Shui… - American Journal of …, 2024 - ncbi.nlm.nih.gov
Screening of potential biomarkers in propofol-induced neurotoxicity via bioinformatics prediction
and experimental verification - PMC Back to Top Skip to main content NIH NLM Logo Access …

[HTML][HTML] 缝隙连接阻断剂对大鼠癫痫后海马涟波振荡能量变化的影响

易妍君, 冉晓, 向敬, 李昕阳, 蒋莉… - Chinese Journal of …, 2021 - ncbi.nlm.nih.gov
缝隙连接阻断剂对大鼠癫痫后海马涟波振荡能量变化的影响- PMC Back to Top Skip to main
content NIH NLM Logo Access keys NCBI Homepage MyNCBI Homepage Main Content Main …

[HTML][HTML] Effect of cypermethrin on the postnatal development of the medulla oblongata and the possible protective role of melatonin in albino rats

MA Al-Gholam, NM Issa - Anatomy & Cell Biology, 2020 - synapse.koreamed.org
Previous studies have shown that cypermethrin (CYP), a broad spectrum pesticide has a
teratogenic effect on rat offspring born to an exposed dam with no information on its effect on …

Метаболізм металів у гіпокампі та роль цинку в патогенезі епілептиформних судом

ОМ Кучковський - Biological Bulletin of Bogdan Chmelnitskiy …, 2016 - search.ebscohost.com
With glutamatergic transmission are сconnect not only convulsive state, but also the
realization of higher integrative functions. Therefore, the development of epilepsy …