Genetics and epigenetics of gastroenteropancreatic neuroendocrine neoplasms

A Mafficini, A Scarpa - Endocrine reviews, 2019 - academic.oup.com
Gastroenteropancreatic (GEP) neuroendocrine neoplasms (NENs) are heterogeneous
regarding site of origin, biological behavior, and malignant potential. There has been a rapid …

Role of biomarker tests for diagnosis of neuroendocrine tumours

J Hofland, WT Zandee, WW de Herder - Nature Reviews Endocrinology, 2018 - nature.com
Neuroendocrine tumours (NETs) are neoplasms that arise from neuroendocrine cells.
Neuroendocrine cells and their tumours can secrete a wide range of amines and …

[HTML][HTML] The landscape of molecular alterations in pancreatic and small intestinal neuroendocrine tumours

A Scarpa - Annales d'endocrinologie, 2019 - Elsevier
Abstract Gastroenteropancreatic Neuroendocrine Neoplasms (GEP-NENs) arise throughout
the gut and feature varying biological behaviour and malignant potential. GEP-NENs include …

A Delphic consensus assessment: imaging and biomarkers in gastroenteropancreatic neuroendocrine tumor disease management

K Oberg, E Krenning, A Sundin, L Bodei… - Endocrine …, 2016 - ec.bioscientifica.com
The complexity of the clinical management of neuroendocrine neoplasia (NEN) is
exacerbated by limitations in imaging modalities and a paucity of clinically useful …

Circulating neuroendocrine tumor biomarkers: past, present and future

P Komarnicki, J Musiałkiewicz, A Stańska… - Journal of Clinical …, 2022 - mdpi.com
Neuroendocrine tumors are a heterogeneous group of neoplasms originating from the
diffuse endocrine system. Depending on primary location and hormonal status, they range in …

A comprehensive assessment of the role of miRNAs as biomarkers in gastroenteropancreatic neuroendocrine tumors

A Malczewska, M Kidd, S Matar, B Kos-Kudla… - …, 2018 - karger.com
Background/Aims: A key issue in neuroendocrine neoplasia management is the
identification of blood signatures that specifically define the activity of a cancer or local tumor …

Clinical presentation and diagnosis of neuroendocrine tumors

AI Vinik, C Chaya - Hematology/Oncology Clinics, 2016 - hemonc.theclinics.com
Neuroendocrine tumors (NETs) are tumors that arise from the diffuse endocrine system.
They are slow-growing and capable of storing and secreting different peptides and …

Clinical epigenetics of neuroendocrine tumors: the road ahead

A Colao, F De Nigris, R Modica, C Napoli - Frontiers in Endocrinology, 2020 - frontiersin.org
Neuroendocrine tumors, or NETs, are cancer originating in neuroendocrine cells. They are
mostly found in the gastrointestinal tract or lungs. Functional NETs are characterized by …

Molecular pathology of well-differentiated gastro-entero-pancreatic neuroendocrine tumors

SL Asa, S La Rosa, O Basturk, V Adsay, M Minnetti… - Endocrine …, 2021 - Springer
Well differentiated neuroendocrine tumors (NETs) arising in the gastrointestinal and
pancreaticobiliary system are the most common neuroendocrine neoplasms. Studies of the …

Circulating plasma microRNA to differentiate Cushing's disease from ectopic ACTH syndrome

Z Belaya, P Khandaeva, L Nonn, A Nikitin… - Frontiers in …, 2020 - frontiersin.org
Corticotropinomas and adrenocorticotropic hormone (ACTH)-secreting neuroendocrine
tumors exhibit differential levels of some microRNAs (miRs) compared to normal tissue …