Microglia are ramified cells that exhibit highly motile processes, which continuously survey
the brain parenchyma and react to any insult to the CNS homeostasis. Although microglia …

When ischemic stroke occurs, oxygen and energy depletion triggers a cascade of events,
including inflammatory responses, glutamate excitotoxicity, oxidative stress, and apoptosis …

Microglia are resident macrophage-like immune cells in the central nervous system (CNS)
and play a vital role in both physiological and pathological conditions, including restoring …

Exposure to stress is an undeniable, but in most cases surmountable, part of life. However,
in certain individuals, exposure to severe or cumulative stressors can lead to an array of …

Aging is a complex biological process that increases the risk of age-related cognitive
degenerative diseases such as dementia, including Alzheimer's disease (AD), Lewy Body …

Arachidonoyl-glycerol (2-AG) and arachidonyl-ethanolamide (AEA) are endocannabinoids
that have been implicated in many physiologic disorders, including obesity, metabolic …

Microglia, the resident immune cells of the central nervous system, mediate brain
homeostasis by controlling neuronal proliferation/differentiation and synaptic activity. In …

Microglial cells are the immune cells in the CNS and represent approximately 10% of the
total brain cell population. Their morphologic characterization by Pio del Rio-Hortega was …

Multiple sclerosis is the most common inflammatory demyelinating disease of the central
nervous system, caused by an autoimmune response against myelin that eventually leads to …

The immune system can be modulated and regulated not only by foreign antigens but also
by other humoral factors and metabolic products, which are able to affect several …