Inflammation: the link between comorbidities, genetics, and Alzheimer's disease

EA Newcombe, J Camats-Perna, ML Silva… - Journal of …, 2018 - Springer
Alzheimer's disease (AD) is a neurodegenerative disorder, most cases of which lack a clear
causative event. This has made the disease difficult to characterize and, thus, diagnose …

A comprehensive overview on osteoporosis and its risk factors

F Pouresmaeili, B Kamalidehghan… - … and clinical risk …, 2018 - Taylor & Francis
Osteoporosis is a bone disorder with remarkable changes in bone biologic material and
consequent bone structural distraction, affecting millions of people around the world from …

Genetics of 35 blood and urine biomarkers in the UK Biobank

N Sinnott-Armstrong, Y Tanigawa, D Amar, N Mars… - Nature …, 2021 - nature.com
Clinical laboratory tests are a critical component of the continuum of care. We evaluate the
genetic basis of 35 blood and urine laboratory measurements in the UK Biobank (n …

[HTML][HTML] Chronic hyperglycemia mediated physiological alteration and metabolic distortion leads to organ dysfunction, infection, cancer progression and other …

B Giri, S Dey, T Das, M Sarkar, J Banerjee… - Biomedicine & …, 2018 - Elsevier
Chronic exposure of glucose rich environment creates several physiological and
pathophysiological changes. There are several pathways by which hyperglycemia …

Diabetes and its effect on bone and fracture healing

H Jiao, E Xiao, DT Graves - Current osteoporosis reports, 2015 - Springer
Diabetes mellitus is a metabolic disorder that increases fracture risk, interferes with bone
formation, and impairs fracture healing. Type 1 diabetes mellitus (T1DM) and type 2 …

Inflammation and oxidative stress in an obese state and the protective effects of gallic acid

PV Dludla, BB Nkambule, B Jack, Z Mkandla, T Mutize… - Nutrients, 2018 - mdpi.com
Metabolic complications in an obese state can be aggravated by an abnormal inflammatory
response and enhanced production of reactive oxygen species. Pro-inflammatory response …

Hyperglycemia associated metabolic and molecular alterations in cancer risk, progression, treatment, and mortality

P Ramteke, A Deb, V Shepal, MK Bhat - Cancers, 2019 - mdpi.com
Cancer and diabetes are amongst the leading causes of deaths worldwide. There is an
alarming rise in cancer incidences and mortality, with approximately 18.1 million new cases …

Impact of polyphenols on inflammatory and oxidative stress factors in diabetes mellitus: nutritional antioxidants and their application in improving antidiabetic therapy

M Krawczyk, I Burzynska-Pedziwiatr, LA Wozniak… - Biomolecules, 2023 - mdpi.com
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycaemia and
oxidative stress. Oxidative stress plays a crucial role in the development and progression of …

Stress hyperglycemia, insulin treatment, and innate immune cells

F Xiu, M Stanojcic, L Diao… - International journal of …, 2014 - Wiley Online Library
Hyperglycemia (HG) and insulin resistance are the hallmarks of a profoundly altered
metabolism in critical illness resulting from the release of cortisol, catecholamines, and …

Vitamin E as a potential interventional treatment for metabolic syndrome: evidence from animal and human studies

SK Wong, KY Chin, FH Suhaimi, F Ahmad… - Frontiers in …, 2017 - frontiersin.org
A constellation of medical conditions inclusive of central obesity, hyperglycemia,
hypertension, and dyslipidemia is known as metabolic syndrome (MetS). The safest option …