HIV-associated neurocognitive disorder

RC Smail, BJ Brew - Handbook of clinical neurology, 2018 - Elsevier
Human immunodeficiency virus (HIV)-associated neurocognitive disorder (HAND) affects
roughly half the HIV-positive population. The symptoms of cognitive slowing, poor …

Aging, comorbidities, and the importance of finding biomarkers for HIV-associated neurocognitive disorders

J Rosenthal, W Tyor - Journal of neurovirology, 2019 - Springer
HIV-associated neurocognitive disorders (HAND) continue to affect a large proportion of
persons living with HIV despite effective viral suppression with combined antiretroviral …

Impact of apolipoprotein E ε4 and HIV on cognition and brain atrophy: antagonistic pleiotropy and premature brain aging

L Chang, M Andres, J Sadino, CS Jiang, H Nakama… - Neuroimage, 2011 - Elsevier
OBJECTIVE: The apolipoprotein E (APOE) ε4 allele may accelerate the progression of HIV
disease, and increase the risk for developing HIV-associated neurocognitive disorder …

Genetic mediators of neurocognitive outcomes in survivors of childhood acute lymphoblastic leukemia

KR Krull, D Bhojwani, HM Conklin, D Pei… - Journal of Clinical …, 2013 - ascopubs.org
Purpose Survivors of childhood acute lymphoblastic leukemia (ALL) are at increased risk for
neurocognitive problems, with significant interindividual variability in outcome. This study …

Risk factors and pathogenesis of HIV-associated neurocognitive disorder: the role of host genetics

IS Olivier, R Cacabelos, V Naidoo - International journal of molecular …, 2018 - mdpi.com
Neurocognitive impairments associated with human immunodeficiency virus (HIV) infection
remain a considerable health issue for almost half the people living with HIV, despite …

Identification of potential mRNA panels for severe acute respiratory syndrome coronavirus 2 (COVID-19) diagnosis and treatment using microarray dataset and …

B Vastrad, C Vastrad, A Tengli - 3 Biotech, 2020 - Springer
The goal of the present investigation is to identify the differentially expressed genes (DEGs)
between SARS-CoV-2 infected and normal control samples to investigate the molecular …

Editorial neuroAIDS review

P Shapshak, P Kangueane, RK Fujimura, D Commins… - Aids, 2011 - journals.lww.com
NeuroAIDS is a disease that incorporates both infectious and degenerative
pathophysiologic pathways. It has a known cause, has several animal models, and is under …

Imaging studies of the HIV-infected brain

L Chang, DK Shukla - Handbook of clinical neurology, 2018 - Elsevier
Human immunodeficiency virus (HIV) enters the brain early after infecting humans and may
remain in the central nervous system despite successful antiretroviral treatment. Many …

Effects of APOE ε4, age, and HIV on glial metabolites and cognitive deficits

L Chang, C Jiang, E Cunningham, S Buchthal… - Neurology, 2014 - AAN Enterprises
Objective: We aimed to evaluate the combined effects of HIV and APOE ε4 allele (s) on glial
metabolite levels, and on known cognitive deficits associated with either condition, across …

Apolipoprotein E4 genotype does not increase risk of HIV-associated neurocognitive disorders

EE Morgan, SP Woods, SL Letendre, DR Franklin… - Journal of …, 2013 - Springer
This is a cross-sectional, observational study to evaluate the hypothesis that HIV-
seropositive (HIV+) apolipoprotein E4 (APOE4) carriers are at increased risk for HIV …