Potential effects of COVID-19 on cytochrome P450-mediated drug metabolism and disposition in infected patients

S Deb, S Arrighi - European journal of drug metabolism and …, 2021 - Springer
Abstract Coronavirus Disease 2019 (COVID-19) has been a global health crisis since it was
first identified in December 2019. In addition to fever, cough, headache, and shortness of …

Regulation of CAR and PXR Expression in Health and Disease

M Daujat-Chavanieu, S Gerbal-Chaloin - Cells, 2020 - mdpi.com
Pregnane X receptor (PXR, NR1I2) and constitutive androstane receptor (CAR, NR1I3) are
members of the nuclear receptor superfamily that mainly act as ligand-activated transcription …

Effects of calcium source, inulin, and lactose on gut‐bone associations in an ovarierectomized rat model

W He, Z Xie, R Thøgersen… - Molecular Nutrition & …, 2022 - Wiley Online Library
Scope Osteoporosis poses a health challenge especially for postmenopausal women. This
study aims to explore nutritional strategies to counteract bone demineralization in …

Bovine mammary epithelial cells can grow and express milk protein synthesis genes at reduced fetal bovine serum concentration

Z Sattari, RB Kjærup, MK Rasmussen… - Cell Biology …, 2024 - Wiley Online Library
Milk proteins produced by lactating cells isolated from bovine mammary tissue can offer a
sustainable solution to the high protein demand of a global growing population. Serum is …

Blueberry and/or banana consumption mitigate arachidonic, cytochrome P450 oxylipin generation during recovery from 75-km cycling: a randomized trial

DC Nieman, ND Gillitt, GY Chen, Q Zhang, W Sha… - Frontiers in …, 2020 - frontiersin.org
Oxylipins are bioactive lipid oxidation products, have vital regulatory roles in numerous
physiological processes including inflammation, and can be impacted by diet. This study …

Bovine satellite cells isolated after 2 and 5 days of tissue storage maintain the proliferative and myogenic capacity needed for cultured meat production

S Skrivergaard, MK Rasmussen, M Therkildsen… - International Journal of …, 2021 - mdpi.com
Cultured meat is an emerging alternative food technology which aims to deliver a more
ethical, sustainable, and healthy muscle-tissue-derived food item compared to conventional …

[HTML][HTML] Hepatic PGC-1α has minor regulatory effect on the liver transcriptome and metabolome during high fat high fructose diet and exercise training

MK Rasmussen, R Thøgersen, PH Lindholm… - Gene, 2023 - Elsevier
The prevalence of non-alcoholic fatty liver diseases (NAFLD) has reached epidemic levels
during recent years and a major driver of NAFLD are diets high in fat and fructose. A …

Fasting augments pyrrolizidine alkaloid-induced hepatotoxicity

J Ma, C Zhang, Y He, X Chen, G Lin - Archives of Toxicology, 2021 - Springer
Pyrrolizidine alkaloids (PAs) are phytotoxins widely present in various natural products and
foodstuffs. The present study aims to investigate the effects of fasting on PA-induced …

[HTML][HTML] Assessing cellular agriculture potential: Population homogeneity and gene expression in cultured bovine mammary epithelial cells

Z Sattari, MK Rasmussen, NA Poulsen, RB Kjærup… - Future Foods, 2024 - Elsevier
Mammary epithelial cells (MEC) are responsible for milk synthesis in the bovine mammary
gland during lactation, and could thereby potentially be used for in-vitro milk components …

Global investigation of cytochrome P450 genes in the chicken genome

J Ren, L Yang, Q Li, Q Zhang, C Sun, X Liu, N Yang - Genes, 2019 - mdpi.com
Cytochrome P450 (CYP) superfamily enzymes are broadly involved in a variety of
physiological and toxicological processes. However, genome-wide analysis of this …