Iron oxide nanoparticles in regenerative medicine and tissue engineering

RP Friedrich, I Cicha, C Alexiou - Nanomaterials, 2021 - mdpi.com
In recent years, many promising nanotechnological approaches to biomedical research
have been developed in order to increase implementation of regenerative medicine and …

The role of dead cell clearance in the etiology and pathogenesis of systemic lupus erythematosus: dendritic cells as potential targets

MHC Biermann, S Veissi, C Maueröder… - Expert review of …, 2014 - Taylor & Francis
Overwhelming apoptosis combined with a deficiency in clearing apoptotic cells is thought to
be an important etiopathogenic event in the autoimmune disease systemic lupus …

Cell death stages in single apoptotic and necrotic cells monitored by Raman microspectroscopy

E Brauchle, S Thude, SY Brucker… - Scientific reports, 2014 - nature.com
Although apoptosis and necrosis have distinct features, the identification and discrimination
of apoptotic and necrotic cell death in vitro is challenging. Immunocytological and …

Cationic antimicrobial peptides cytotoxicity on mammalian cells: an analysis using therapeutic index integrative concept

M Bacalum, M Radu - International Journal of Peptide Research and …, 2015 - Springer
Antimicrobial peptides (AMPs) represent a class of molecules synthesized by different
organisms as an ancient innate defense mechanism against different pathogens like …

A high-throughput real-time imaging technique to quantify NETosis and distinguish mechanisms of cell death in human neutrophils

S Gupta, DW Chan, KJ Zaal… - The Journal of Immunology, 2018 - journals.aai.org
Neutrophils play a key role in host defenses and have recently been implicated in the
pathogenesis of autoimmune diseases by various mechanisms, including formation of …

Selection of potential iron oxide nanoparticles for breast cancer treatment based on in vitro cytotoxicity and cellular uptake

JM Poller, J Zaloga, E Schreiber… - International journal …, 2017 - Taylor & Francis
Superparamagnetic iron oxide nanoparticles (SPIONs) are promising tools for the treatment
of different diseases. Their magnetic properties enable therapies involving magnetic drug …

Flow cytometry for intracellular SPION quantification: specificity and sensitivity in comparison with spectroscopic methods

RP Friedrich, C Janko, M Poettler, P Tripal… - International journal …, 2015 - Taylor & Francis
Due to their special physicochemical properties, iron nanoparticles offer new promising
possibilities for biomedical applications. For bench to bedside translation of super …

Cellular effects of paclitaxel-loaded iron oxide nanoparticles on breast cancer using different 2D and 3D cell culture models

S Lugert, H Unterweger, M Mühlberger… - International journal …, 2019 - Taylor & Francis
Background Magnetic drug targeting (MDT) is an effective alternative for common drug
applications, which reduces the systemic drug load and maximizes the effect of, eg …

Aggregated NETs sequester and detoxify extracellular histones

J Knopf, M Leppkes, G Schett, M Herrmann… - Frontiers in …, 2019 - frontiersin.org
In response to various infectious and sterile stimuli neutrophils release chromatin decorated
with bactericidal proteins, referred to as NETs. Their scaffolds are formed from chromatin …

Cellular spion uptake and toxicity in various head and neck cancer cell lines

M Balk, T Haus, J Band, H Unterweger, E Schreiber… - Nanomaterials, 2021 - mdpi.com
Superparamagnetic iron oxide nanoparticles (SPIONs) feature distinct magnetic properties
that make them useful and effective tools for various diagnostic, therapeutic and theranostic …