Noonan syndrome (NS) and related Noonan syndrome with multiple lentigines (NSML)
contribute to the pathogenesis of human diseases in the RASopathy family. This family of …

Objective: In vivo studies suggest that intestinal barrier integrity is dependent on
mitochondrial ATP production. Here, we aim to provide mechanistic support, using an in vitro …

Abstract Both RhoA/ROCK and Raf-1/CK2 pathway play essential roles in cell proliferation,
apoptosis, differentiation, and multiple other common cellular functions. We previously …

The aim of study was to investigate proliferation and differentiation capacities of Hanwoo
myosatellite cells for the development of Hanwoo cell cultures. From P1 to P19, the number …

To date, most in vitro toxicity testing has focused on acute effects of compounds at high
concentrations. This testing strategy does not reflect real-life exposures, which might …

Mitochondria play a central role in cellular energy production, and their dysfunction can
trigger a compensatory increase in glycolytic flux to sustain cellular ATP levels. Here, we …

Macroautophagy is a conserved eukaryotic process for degradation of cellular components
in response to lack of nutrients. It is involved in the development of diseases, notably cancer …

It has been reported that Ywhah (14-3-3η) reduces glycolysis. However, it remains unclear
about the downstream mechanism by which glycolysis is regulated by 14-3-3η in cardiac …

It is often desirable to characterise the morphology of myogenic cultures. To achieve this, the
surface area of myotubes is often quantified, along with the nuclear fusion index (NFI) …

Rationale Asthma is a chronic inflammatory disease of the airways that involves crosstalk
between myeloid-derived regulatory cells (MDRCs) and CD4+ T cells. Although small …