Centella asiatica: phytochemistry and mechanisms of neuroprotection and cognitive enhancement

NE Gray, A Alcazar Magana, P Lak, KM Wright… - Phytochemistry …, 2018 - Springer
This review describes in detail the phytochemistry and neurological effects of the medicinal
herb Centella asiatica (L.) Urban. C. asiatica is a small perennial plant that grows in moist …

[PDF][PDF] A review on medicinal properties of Centella asiatica

V Prakash, N Jaiswal, M Srivastava - Asian J Pharm Clin Res, 2017 - researchgate.net
Plant-based drug discovery has drawn the attention of researchers, especially the one used
as traditional medicines. Centella asiatica is traditional Ayurveda medicine widely used in …

[HTML][HTML] Recent updates in neuroprotective and neuroregenerative potential of Centella asiatica

Y Lokanathan, N Omar, NNA Puzi, A Saim… - The Malaysian journal …, 2016 - ncbi.nlm.nih.gov
Centella asiatica, locally well known in Malaysia as pegaga, is a traditional herb that has
been used widely in Ayurvedic medicine, traditional Chinese medicine, and in the traditional …

Synthetic and Natural Inhibitors of Phospholipases A2: Their Importance for Understanding and Treatment of Neurological Disorders

WY Ong, T Farooqui, G Kokotos… - ACS chemical …, 2015 - ACS Publications
Phospholipases A2 (PLA2) are a diverse group of enzymes that hydrolyze membrane
phospholipids into arachidonic acid and lysophospholipids. Arachidonic acid is metabolized …

Centella Asiatica Improves Memory and Promotes Antioxidative Signaling in 5XFAD Mice

DG Matthews, M Caruso, CF Murchison, JY Zhu… - Antioxidants, 2019 - mdpi.com
Centella asiatica (CA) herb is a traditional medicine, long reputed to provide cognitive
benefits. We have reported that CA water extract (CAW) treatment improves cognitive …

[HTML][HTML] Current updates on Centella asiatica: phytochemistry, pharmacology and traditional uses

DC Roy, SK Barman, MM Shaik - Medicinal Plant Research, 2013 - hortherbpublisher.com
Plants have been demonstrated extraordinary source of medicine, and recently focus on
medicinal plant research has increased. Centella asiatica is well known for its traditional …

Centella asiatica attenuates amyloid-β-induced oxidative stress and mitochondrial dysfunction

NE Gray, H Sampath, JA Zweig… - Journal of …, 2015 - content.iospress.com
Background: We previously showed that a water extract of the medicinal plant Centella
asiatica (CAW) attenuates amyloid-ß (Aß)-induced cognitive deficits in vivo, and prevents Aß …

Phytocompounds from Himalayan Medicinal Plants as Potential Drugs to Treat Multidrug-Resistant Salmonella typhimurium: An In Silico Approach

J Mehta, R Rolta, D Salaria, O Awofisayo, OA Fadare… - Biomedicines, 2021 - mdpi.com
Medicinal plants can be used as natural therapeutics to treat diseases in humans. Enteric
bacteria possess efflux pumps to remove bile salts from cells to avoid potential membrane …

Role of Cytosolic Phospholipase A2 in Oxidative and Inflammatory Signaling Pathways in Different Cell Types in the Central Nervous System

GY Sun, DY Chuang, Y Zong, J Jiang, JCM Lee… - Molecular …, 2014 - Springer
Abstract Phospholipases A 2 (PLA 2 s) are important enzymes for the metabolism of fatty
acids in membrane phospholipids. Among the three major classes of PLA 2 s in the …

Asiaticoside, a component of Centella asiatica, inhibits melanogenesis in B16F10 mouse melanoma

KJ Kwon, S Bae, K Kim, IS An… - Molecular …, 2014 - spandidos-publications.com
Melanogenesis is the process of generating pigmentation via melanin synthesis and
delivery. Three key enzymes, tyrosinase, tyrosinase‑related protein 1 (TRP1) and TRP2 …