Advances in laser speckle imaging: from qualitative to quantitative hemodynamic assessment

MM Qureshi, N Allam, J Im, HS Kwon… - Journal of …, 2024 - Wiley Online Library
Laser speckle imaging (LSI) techniques have emerged as a promising method for
visualizing functional blood vessels and tissue perfusion by analyzing the speckle patterns …

[HTML][HTML] Visualizing vasculature and its response to therapy in the tumor microenvironment

Q Lin, PL Choyke, N Sato - Theranostics, 2023 - ncbi.nlm.nih.gov
Tumor vasculature plays a critical role in the progression and metastasis of tumors,
antitumor immunity, drug delivery, and resistance to therapies. The morphological and …

3D transcranial ultrasound localization microscopy for discrimination between ischemic and hemorrhagic stroke in early phase

A Chavignon, V Hingot, C Orset, D Vivien… - Scientific Reports, 2022 - nature.com
Early diagnosis is a critical part of the emergency care of cerebral hemorrhages and
ischemia. A rapid and accurate diagnosis of strokes reduces the delays to appropriate …

Binary dose level classification of tumour microvascular response to radiotherapy using artificial intelligence analysis of optical coherence tomography images

A Majumdar, N Allam, WJ Zabel, V Demidov… - Scientific Reports, 2022 - nature.com
The dominant consequence of irradiating biological systems is cellular damage, yet
microvascular damage begins to assume an increasingly important role as the radiation …

Radiation-induced alterations in multi-layered, in-vitro skin models detected by optical coherence tomography and histological methods

L Bromberger, B Heise, K Felbermayer… - PloS one, 2023 - journals.plos.org
Background Inflammatory skin reactions and skin alterations are still a potential side effect in
radiation therapy (RT), which also need attention for patients' health care. Method In a pre …

Low-cost 3D-printed tools towards robust longitudinal multi-modal pre-clinical imaging

N Allam, IA Vitkin, E Taylor - bioRxiv, 2023 - biorxiv.org
Window chamber models enable a range of preclinical in-vivo optical studies with high
spatial resolution and contrast, most notably probing the tumour microenvironment (TME) …

Author Spotlight: Integrating High-Resolution Intravital Imaging and MRI to Enhance Stereotactic Body Radiation Therapy Planning

WJ Zabel, N Allam, HAC Sanchez, W Foltz… - JoVE (Journal of …, 2024 - jove.com
Preclinical intravital imaging such as microscopy and optical coherence tomography have
proven to be valuable tools in cancer research for visualizing the tumor microenvironment …

Quantifying 3D Tumor Microvascular Heterogeneity via Super-resolution Ultrasound Imaging to Categorize and Characterize Microvascular Subgroups in U87 …

J Yin, F Dong, J An, J Zhang… - 2023 IEEE International …, 2023 - ieeexplore.ieee.org
Cancer treatment response has traditionally been monitored by measuring tumor volume
without considering tumor microvascular heterogeneity (TMH), which is known to profoundly …

The effects of radiotherapy on tumour microvasculature: insights from optical coherence angiography and dynamic contrast-enhanced MR imaging towards adaptive …

N Allam, WJ Zabel, V Demidov, B Jones… - Tissue Optics and …, 2022 - spiedigitallibrary.org
Stereotactic body radiotherapy (SBRT) shows promise for increasing local tumour control for
many of the most lethal cancer types including pancreatic ductal carcinoma (PDA) …

Bronchial Sleeve Resection After Induction Therapy: Roll Up Your Sleeves

WS Brandt, V Puri - The Annals of thoracic surgery, 2022 - pubmed.ncbi.nlm.nih.gov
Bronchial Sleeve Resection After Induction Therapy: Roll Up Your Sleeves Bronchial Sleeve
Resection After Induction Therapy: Roll Up Your Sleeves Ann Thorac Surg. 2022 …