Impurity retention and pharmaceutical solid solutions: visualizing the effect of impurities on dissolution and growth using dyed crystals
A Nong, C Schleper, A Martin, M Paolello… - …, 2024 - pubs.rsc.org
Pharmaceutical solid solutions are gaining increased interest as alternatives to salts and co-
crystals for the enhancement of drug solubility and dissolution kinetics. Industrially, they are …
crystals for the enhancement of drug solubility and dissolution kinetics. Industrially, they are …
Thermodynamic Stability Transitions and Coexistence of Two Polymorphs via Crystalline Solid Solutions: The TX Phase Diagram of Salicylic Acid and 2, 3 …
SS Mohajerani, M Paolello, B Linehan… - Crystal Growth & …, 2024 - ACS Publications
The thermodynamically stable phases of salicylic acid (SA) and 2, 3-dihydroxybenzoic acid
(23DHBA) have been determined experimentally in a TX phase diagram from 25° C to …
(23DHBA) have been determined experimentally in a TX phase diagram from 25° C to …
Aqueous solution and solid-state behaviour of l-homophenylalanine: experiment, modelling, and DFT calculations
In the present study, the solid-state and aqueous solubility behaviour of L-
homophenylalanine (L-Hpa) is explored. Different characterization techniques such as TG …
homophenylalanine (L-Hpa) is explored. Different characterization techniques such as TG …
A Mathematically Simplified Solid–Solid–Liquid Ternary Phase Diagram with Tie-Lines for Early Process Development Validated by Chiral Resolution of Racemic …
DE Pratama, CY Huang, T Lee - Industrial & Engineering …, 2024 - ACS Publications
Predictions of the purity and yield of a solid product by solid–liquid separation, such as
reaction crystallization and extraction, can accurately be captured if the solid–solid–liquid …
reaction crystallization and extraction, can accurately be captured if the solid–solid–liquid …
Solid Phase and Stability Investigation of a Co-Crystal in the l-Valine/l-Leucine System
V Tenberg, M Stein, H Lorenz - Crystals, 2023 - mdpi.com
Some amino acid systems are known to exhibit solid solution and/or co-crystal behavior
upon crystallization, which significantly affects their phase diagrams and complicates the …
upon crystallization, which significantly affects their phase diagrams and complicates the …
Separation of solid solutions using counter-current crystallization: improved operation through antisolvents
V Tenberg - 2023 - repo.bibliothek.uni-halle.de
Separating different components present in a solid solution is a challenging purification task.
The components cannot be isolated in a single crystallization step. Crystallizationbased …
The components cannot be isolated in a single crystallization step. Crystallizationbased …