Complex natural products bearing strained cyclobutane subunits, including terpenoids,
alkaloids and steroids, not only display fascinating architectures, but also show potent …

Covering: 2000–2018 In this review, we highlight recent examples of natural product total
syntheses employing transition metal-mediated/catalyzed carbonylative cyclization …

The exploration of the complex chemical diversity of bicyclo [n. 1.1] alkanes and their use as
benzene bioisosteres has garnered significant attention over the past two decades …

Given the importance of cyclic frameworks in molecular scaffolds and drug discovery, it is
intriguing to precisely forge and manipulate ring systems in synthetic chemistry. In this field …

Here we report a contractive synthesis of multisubstituted cyclobutanes containing multiple
stereocenters from readily accessible pyrrolidines using iodonitrene chemistry. Mediated by …

Covering: July 2012 to December 2019 Over the last seven years, expanding research
efforts focused on sesterterpenoids has led to the isolation, identification, and …

Conspectus Native to the Asia-Pacific region and widely applied in traditional Chinese
medicine, the genus Daphniphyllum has produced over 330 known Daphniphyllum …

Comprehensive Summary Chemical investigation of Hedyosmum orientale led to the
identification of two terpenoid derivatives, dyosmunoids A and B (1 and 2) featuring two …

We report the first enantioselective total synthesis of diterpenoid randainin D, which
possesses a hydroazulenone core with a β-substituted butenolide moiety on the …

Sesterterpenoids are a very rare class of important natural products. Three new skeletal
spiro sesterterpenoids, named orientanoids A–C (1–3), were isolated from Hedyosmum …