Lynch syndrome, which is now recognized as the most common hereditary colorectal cancer
condition, is characterized by the predisposition to a spectrum of cancers, primarily …

The dynamic and versatile nature of diseases such as cancer has been a pivotal challenge
for developing efficient and safe therapies. Cancer treatments using a single therapeutic …

Here, we summarise the unresolved debate about p value and its dichotomisation. We
present the statement of the American Statistical Association against the misuse of statistical …

Lung cancer (LC) is the leading cause of cancer mortality, with more than 1 million deaths
worldwide every year. 1, 2 There are two major forms of LC disease: nonsmall cell LC …

A new non-invasive and potentially inexpensive frontier in the diagnosis of cancer relies on
the detection of volatile organic compounds (VOCs) in exhaled breath samples. Breath can …

Microarray-based gene expression profiling has had a major effect on our understanding of
breast cancer. Breast cancer is now perceived as a heterogeneous group of different …

Breast cancer is a heterogeneous disease, comprising multiple entities associated with
distinctive histological and biological features, clinical presentations and behaviours and …

Patient-derived xenograft (PDX) models of a growing spectrum of cancers are rapidly
supplanting long-established traditional cell lines as preferred models for conducting basic …

This review discusses the results of DNA microarray signatures in breast cancer. These
signatures have been useful in the classification of breast cancers, and they have an …

Context Prediction of high probability of survival from standard cancer treatments is
fundamental for individualized cancer treatment strategies. Objective To develop a predictor …