Oxidative stress as key player in severe acute respiratory syndrome coronavirus (SARS-CoV) infection
L Delgado-Roche, F Mesta - Archives of medical research, 2020 - Elsevier
The emergence of viral respiratory pathogens with pandemic potential, such as severe acute
respiratory syndrome coronavirus (SARS-CoV), the pathogenic agent of Covid-19, represent …
respiratory syndrome coronavirus (SARS-CoV), the pathogenic agent of Covid-19, represent …
Human coronaviruses and other respiratory viruses: underestimated opportunistic pathogens of the central nervous system?
M Desforges, A Le Coupanec, P Dubeau, A Bourgouin… - viruses, 2019 - mdpi.com
Respiratory viruses infect the human upper respiratory tract, mostly causing mild diseases.
However, in vulnerable populations, such as newborns, infants, the elderly and immune …
However, in vulnerable populations, such as newborns, infants, the elderly and immune …
[HTML][HTML] Viral presence and immunopathology in patients with lethal COVID-19: a prospective autopsy cohort study
B Schurink, E Roos, T Radonic, E Barbe… - The Lancet …, 2020 - thelancet.com
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) targets
multiple organs and causes severe coagulopathy. Histopathological organ changes might …
multiple organs and causes severe coagulopathy. Histopathological organ changes might …
A comparative study on the clinical features of coronavirus 2019 (COVID-19) pneumonia with other pneumonias
D Zhao, F Yao, L Wang, L Zheng, Y Gao… - Clinical infectious …, 2020 - academic.oup.com
Background A novel coronavirus (COVID-19) has raised world concern since it emerged in
Wuhan, China in December 2019. The infection may result in severe pneumonia with …
Wuhan, China in December 2019. The infection may result in severe pneumonia with …
[HTML][HTML] IL-6: Relevance for immunopathology of SARS-CoV-2
EO Gubernatorova, EA Gorshkova, AI Polinova… - Cytokine & growth factor …, 2020 - Elsevier
COVID-19 mortality is strongly associated with the development of severe pneumonia and
acute respiratory distress syndrome with the worst outcome resulting in cytokine release …
acute respiratory distress syndrome with the worst outcome resulting in cytokine release …
Mitochondria and microbiota dysfunction in COVID-19 pathogenesis
The COVID-19 pandemic caused by the coronavirus (SARS-CoV-2) has taken the world by
surprise into a major crisis of overwhelming morbidity and mortality. This highly infectious …
surprise into a major crisis of overwhelming morbidity and mortality. This highly infectious …
IFN-I response timing relative to virus replication determines MERS coronavirus infection outcomes
Type 1 IFNs (IFN-I) generally protect mammalian hosts from virus infections, but in some
cases, IFN-I is pathogenic. Because IFN-I is protective, it is commonly used to treat virus …
cases, IFN-I is pathogenic. Because IFN-I is protective, it is commonly used to treat virus …
Recombinant protein vaccines, a proven approach against coronavirus pandemics
With the COVID-19 pandemic now ongoing for close to a year, people all over the world are
still waiting for a vaccine to become available. The initial focus of accelerated global …
still waiting for a vaccine to become available. The initial focus of accelerated global …
Complement activation contributes to severe acute respiratory syndrome coronavirus pathogenesis
Acute respiratory distress syndrome (ARDS) is immune-driven pathologies that are
observed in severe cases of severe acute respiratory syndrome coronavirus (SARS-CoV) …
observed in severe cases of severe acute respiratory syndrome coronavirus (SARS-CoV) …
Cardiovascular complications in patients with COVID-19: consequences of viral toxicities and host immune response
Abstract Purpose of Review Coronavirus disease of 2019 (COVID-19) is a cause of
significant morbidity and mortality worldwide. While cardiac injury has been demonstrated in …
significant morbidity and mortality worldwide. While cardiac injury has been demonstrated in …