Crosstalk of inflammatory cytokines within the breast tumor microenvironment

O Habanjar, R Bingula, C Decombat… - International journal of …, 2023 - mdpi.com
Several immune and immunocompetent cells, including dendritic cells, macrophages,
adipocytes, natural killer cells, T cells, and B cells, are significantly correlated with the …

The tumor-promoting flow of cells into, within and out of the tumor site: regulation by the inflammatory axis of TNFα and chemokines

A Ben-Baruch - Cancer Microenvironment, 2012 - Springer
Tumors are dynamic organs, in which active processes of cell motility affect disease course
by regulating the composition of cells at the tumor site. While sub-populations of tumor …

TNF-α is a potential therapeutic target to overcome sorafenib resistance in hepatocellular carcinoma

W Tan, X Luo, W Li, J Zhong, J Cao, S Zhu, X Chen… - …, 2019 - thelancet.com
Background The role of tumor necrosis factor alpha (TNF-α) in targeted therapy for
hepatocellular carcinoma (HCC) remains largely unknown. The current study aimed to …

Rhus coriaria suppresses angiogenesis, metastasis and tumor growth of breast cancer through inhibition of STAT3, NFκB and nitric oxide pathways

H El Hasasna, A Saleh, HA Samri, K Athamneh… - Scientific reports, 2016 - nature.com
Recently, we reported that Rhus coriaria exhibits anticancer activities by promoting cell cycle
arrest and autophagic cell death of the metastatic triple negative MDA-MB-231 breast cancer …

Efficient Polysulfide‐Based Nanotheranostics for Triple‐Negative Breast Cancer: Ratiometric Photoacoustics Monitored Tumor Microenvironment‐Initiated H2S …

J Li, X Li, Y Yuan, Q Wang, L Xie, Y Dai, W Wang, L Li… - Small, 2020 - Wiley Online Library
The incidence of triple‐negative breast cancer (TNBC) is difficult to predict, and TNBC has a
high mortality rate among women worldwide. In this study, a theranostics approach is …

Apoptosis, angiogenesis, inflammation, and oxidative stress: basic interactions in patients with early and metastatic breast cancer

EA Hamed, MM Zakhary, DW Maximous - Journal of cancer research and …, 2012 - Springer
Purpose Breast cancer (BC) is a complex, multi-stage disease involving deregulation of
different signaling cascades. The present study was conducted to determine the extent of …

Zerumbone suppresses IL‐1β‐induced cell migration and invasion by inhibiting IL‐8 and MMP‐3 expression in human triple‐negative breast cancer cells

J Han, SY Bae, SJ Oh, J Lee, JH Lee… - Phytotherapy …, 2014 - Wiley Online Library
Inflammation is a key regulatory process in cancer development. Prolonged exposure of
breast tumor cells to inflammatory cytokines leads to epithelial‐mesenchymal transition …

[HTML][HTML] Antagonists of growth hormone-releasing hormone suppress in vivo tumor growth and gene expression in triple negative breast cancers

R Perez, AV Schally, I Vidaurre, R Rincon, NL Block… - Oncotarget, 2012 - ncbi.nlm.nih.gov
This study evaluated the effects of a modern antagonistic analog of GHRH on tumor growth
and on expression of inflammatory cytokine genes in two models of human triple negative …

The marine natural product pseudopterosin blocks cytokine release of triple-negative breast cancer and monocytic leukemia cells by inhibiting NF-κB signaling

J Sperlich, R Kerr, N Teusch - Marine drugs, 2017 - mdpi.com
Pseudopterosins are a group of marine diterpene glycosides which possess an array of
biological activities including anti-inflammatory effects. However, despite the striking in vivo …

Differences in the expression of TLRs and inflammatory cytokines in pre-eclamptic compared with healthy pregnant women

F Dabagh-Gorjani, F Anvari, J Zolghadri… - Iranian Journal of …, 2014 - iji.sums.ac.ir
Background: Preeclampsia (PE) is one of the most complex and life-threatening pregnancy
disorders and is considered as a major cause of mortality among mothers and fetuses …