Current insights on biomarkers in lupus nephritis: a systematic review of the literature

L Palazzo, J Lindblom, C Mohan, I Parodis - Journal of Clinical Medicine, 2022 - mdpi.com
Lupus nephritis (LN) is a major cause of morbidity and mortality among patients with
systemic lupus erythematosus (SLE). However, promising emerging biomarkers pave the …

Lupus nephritis biomarkers: a critical review

FK Alduraibi, GC Tsokos - International Journal of Molecular Sciences, 2024 - mdpi.com
Lupus nephritis (LN), a major complication in individuals diagnosed with systemic lupus
erythematosus, substantially increases morbidity and mortality. Despite marked …

V‐Set Immunoglobulin Domain–Containing Protein 4 as a Novel Serum Biomarker of Lupus Nephritis and Renal Pathology Activity

C Tang, S Zhang, A Teymur, B Yang… - Arthritis & …, 2023 - Wiley Online Library
Objective To discover novel serum biomarkers that have diagnostic or predictive value in
lupus nephritis (LN). Methods Using a quantitative protein microarray, we screened for high …

Artificial intelligence and high-dimensional technologies in the theragnosis of systemic lupus erythematosus

KN Yaung, JG Yeo, P Kumar, M Wasser… - The Lancet …, 2023 - thelancet.com
Systemic lupus erythematosus is a complex, systemic autoimmune disease characterised by
immune dysregulation. Pathogenesis is multifactorial, contributing to clinical heterogeneity …

Applying 12 machine learning algorithms and Non-negative Matrix Factorization for robust prediction of lupus nephritis

L Mou, Y Lu, Z Wu, Z Pu, X Huang, M Wang - Frontiers in Immunology, 2024 - frontiersin.org
Lupus nephritis (LN) is a challenging condition with limited diagnostic and treatment options.
In this study, we applied 12 distinct machine learning algorithms along with Non-negative …

[HTML][HTML] Urinary Immune Complexes Reflect Renal Pathology in Lupus Nephritis

C Tang, A Teymur, T Wu - Diagnostics, 2024 - mdpi.com
Background/Objectives: Lupus nephritis (LN) is a serious complication of systemic lupus
erythematosus (SLE), involving immune complex deposition in the kidneys. While renal …

Identification of PHACTR4 as A New Biomarker for Diabetic Nephropathy and Its Correlation with Glomerular Endothelial Dysfunction and Immune Infiltration.

B Yu, M Meng, T Li, Y Shi - Iranian Journal of Kidney …, 2023 - search.ebscohost.com
Introduction. The pathophysiology of diabetic nephropathy (DN) is fundamentally dependent
on glomerular endothelial cells (GECs), which are a crucial portion of the glomerular …

Biomarkers for systemic lupus erythematosus: A scoping review

S Zhang, R Xu, L Kang - Immunity, Inflammation and Disease, 2024 - Wiley Online Library
Background In recent years, newly discovered potential biomarkers have great research
potential in the diagnosis, disease activity prediction, and treatment of systemic lupus …

Pan-Cancer Analysis of P3H1 and Experimental Validation in Renal Clear Cell Carcinoma

Y Li, T Wang, F Jiang - Applied Biochemistry and Biotechnology, 2024 - Springer
Abstract Prolyl 3-hydroxylase 1 (P3H1) has been implicated in cancer development, but no
pan-cancer analysis has been conducted on P3H1. In this study, for the first time, aspects …

New biomarkers for the diagnosis and treatment of systemic lupus erythematosus

A Perl, N Agmon-Levin, JC Crispín… - Frontiers in …, 2022 - frontiersin.org
glomerular S100A8 staining in class IV LN patients over controls (10). S100A8 has been
identified as a DEG with overexpression in kidneys of LN patients (10). Mass spectroscopy …