Microfluidic-based technologies for diagnosis, prevention, and treatment of COVID-19: recent advances and future directions
The COVID-19 pandemic has posed significant challenges to existing healthcare systems
around the world. The urgent need for the development of diagnostic and therapeutic …
around the world. The urgent need for the development of diagnostic and therapeutic …
Targeting genomic SARS-CoV-2 RNA with siRNAs allows efficient inhibition of viral replication and spread
A promising approach to tackle the severe acute respiratory syndrome coronavirus-2 (SARS-
CoV-2) could be small interfering (si) RNAs. So far it is unclear, which viral replication steps …
CoV-2) could be small interfering (si) RNAs. So far it is unclear, which viral replication steps …
Keeping up with the COVID's—Could siRNA‐based antivirals be a part of the answer?
Abstract Coronavirus disease 2019 (COVID‐19) is a highly contagious viral disease caused
by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). This deadly infection …
by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). This deadly infection …
Pulmonary siRNA delivery with sophisticated amphiphilic poly (spermine acrylamides) for the treatment of lung fibrosis
RNA interference (RNAi) is an efficient strategy to post‐transcriptionally silence gene
expression. While all siRNA drugs on the market target the liver, the lung offers a variety of …
expression. While all siRNA drugs on the market target the liver, the lung offers a variety of …
XNAzymes targeting the SARS-CoV-2 genome inhibit viral infection
PP Gerber, MJ Donde, NJ Matheson… - Nature …, 2022 - nature.com
The unprecedented emergence and spread of SARS-CoV-2, the coronavirus responsible for
the COVID-19 pandemic, underscores the need for diagnostic and therapeutic technologies …
the COVID-19 pandemic, underscores the need for diagnostic and therapeutic technologies …
Selection and validation of siRNAs preventing uptake and replication of SARS-CoV-2
M Friedrich, G Pfeifer, S Binder, A Aigner… - … in bioengineering and …, 2022 - frontiersin.org
In 2019, the novel highly infectious severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) outbreak rapidly led to a global pandemic with more than 346 million confirmed …
CoV-2) outbreak rapidly led to a global pandemic with more than 346 million confirmed …
[HTML][HTML] Ex vivo and in vivo suppression of SARS-CoV-2 with combinatorial AAV/RNAi expression vectors
Despite rapid development and deployment of vaccines against severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), clinically relevant modalities to curb the pandemic …
syndrome coronavirus 2 (SARS-CoV-2), clinically relevant modalities to curb the pandemic …
Potential of siRNA in COVID-19 therapy: Emphasis on in silico design and nanoparticles based delivery
Small interfering RNA (siRNA)-mediated mRNA degradation approach have imparted its
eminence against several difficult-to-treat genetic disorders and other allied diseases. Viral …
eminence against several difficult-to-treat genetic disorders and other allied diseases. Viral …
Designing Cell Delivery Peptides and SARS-CoV-2-Targeting Small Interfering RNAs: A Comprehensive Bioinformatics Study with Generative Adversarial Network …
RD González, S Simões, L Ferreira… - Molecular …, 2023 - ACS Publications
Nucleic acid technologies with designed intracellular delivery systems are some of the most
promising therapies of the future. Small interfering (si) RNAs inhibit gene expression and …
promising therapies of the future. Small interfering (si) RNAs inhibit gene expression and …
COVID-19 Virus Structural Details: Optical and Electrochemical Detection
The increasing viral species have ruined people's health and the world's economy.
Therefore, it is urgent to design bio-responsive materials to provide a vast platform for …
Therefore, it is urgent to design bio-responsive materials to provide a vast platform for …