[HTML][HTML] The role of insufficient sleep and circadian misalignment in obesity

JP Chaput, AW McHill, RC Cox, JL Broussard… - Nature Reviews …, 2023 - nature.com
Traditional risk factors for obesity and the metabolic syndrome, such as excess energy
intake and lack of physical activity, cannot fully explain the high prevalence of these …

Circadian rhythms and disorders of the timing of sleep

N Meyer, AG Harvey, SW Lockley, DJ Dijk - The Lancet, 2022 - thelancet.com
The daily alternation between sleep and wakefulness is one of the most dominant features
of our lives and is a manifestation of the intrinsic 24 h rhythmicity underlying almost every …

[HTML][HTML] Circadian disruption and human health

AB Fishbein, KL Knutson, PC Zee - The Journal of clinical …, 2021 - Am Soc Clin Investig
Circadian disruption is pervasive and can occur at multiple organizational levels,
contributing to poor health outcomes at individual and population levels. Evidence points to …

Gut microbiota and human NAFLD: disentangling microbial signatures from metabolic disorders

J Aron-Wisnewsky, C Vigliotti, J Witjes, P Le… - Nature Reviews …, 2020 - nature.com
Gut microbiota dysbiosis has been repeatedly observed in obesity and type 2 diabetes
mellitus, two metabolic diseases strongly intertwined with non-alcoholic fatty liver disease …

Molecular mechanisms and physiological importance of circadian rhythms

A Patke, MW Young, S Axelrod - Nature reviews Molecular cell biology, 2020 - nature.com
To accommodate daily recurring environmental changes, animals show cyclic variations in
behaviour and physiology, which include prominent behavioural states such as sleep–wake …

Sleep timing, sleep consistency, and health in adults: a systematic review

JP Chaput, C Dutil, R Featherstone… - Applied Physiology …, 2020 - cdnsciencepub.com
The objective of this systematic review was to examine the associations between sleep
timing (eg, bedtime/wake-up time, midpoint of sleep), sleep consistency/regularity (eg, intra …

[HTML][HTML] Chronotype and social jetlag: a (self-) critical review

T Roenneberg, LK Pilz, G Zerbini, EC Winnebeck - Biology, 2019 - mdpi.com
The Munich ChronoType Questionnaire (MCTQ) has now been available for more than 15
years and its original publication has been cited 1240 times (Google Scholar, May 2019) …

[HTML][HTML] Biological rhythm and chronotype: new perspectives in health

A Montaruli, L Castelli, A Mulè, R Scurati, F Esposito… - Biomolecules, 2021 - mdpi.com
The circadian rhythm plays a fundamental role in regulating biological functions, including
sleep–wake preference, body temperature, hormonal secretion, food intake, and cognitive …

Circadian clocks and insulin resistance

DJ Stenvers, FAJL Scheer, P Schrauwen… - Nature Reviews …, 2019 - nature.com
Insulin resistance is a main determinant in the development of type 2 diabetes mellitus and a
major cause of morbidity and mortality. The circadian timing system consists of a central …

Crosstalk between metabolism and circadian clocks

H Reinke, G Asher - Nature Reviews Molecular Cell Biology, 2019 - nature.com
Humans, like all mammals, partition their daily behaviour into activity (wakefulness) and rest
(sleep) phases that differ largely in their metabolic requirements. The circadian clock …