Significance and considerations of establishing standardized critical values for critical size defects in animal models of bone tissue regeneration

J Wei, X Chen, Y Xu, L Shi, M Zhang, M Nie, X Liu - Heliyon, 2024 - cell.com
Establishing animal models with critical size defects (CSDs) is critical for conducting
experimental investigations engineering of bone tissue regeneration. Currently, a …

Optimizing Orthopaedic Bone Plates for Directed Energy Deposition with Generative Design and Topological Optimization Approaches

W Xu, F Liu, A Nassehi - Procedia CIRP, 2024 - Elsevier
Abstract Directed Energy Deposition (DED), a metal additive manufacturing technique,
shows promise for future orthopaedic applications, especially in bone plate manufacturing …

Refining Bone Plate Design for Proximal Tibia Fractures: A Comparative Evaluation of Methods and Outcomes in Patient-Specific Approaches

W Xu, F Liu, Y Xu, R Quan, A Nassehi - International Conference on …, 2024 - Springer
This study aims to assess and rank the effectiveness of 3D reconstruction, parametric
design, and generative design in creating cost-effective, timely, and clinically appropriate …