Changes in the composition of gut-associated microbial communities are associated with
many human illnesses, but the factors driving dysbiosis remain incompletely understood …

Tripartite efflux pumps and the related type 1 secretion systems (T1SSs) in Gram-negative
organisms are diverse in function, energization, and structural organization. They form …

The gut microbiome is critical in providing resistance against colonization by exogenous
microorganisms. The mechanisms via which the gut microbiota provide colonization …

Background Probiotics are live microorganisms that, when administered in adequate
amounts, confer a health benefit on the host, are now accepted as suitable alternatives to …

Although diet has long been known to contribute to the pathogenesis of cardiovascular
disease (CVD), research over the past decade has revealed an unexpected interplay …

Emerging evidence strongly suggest that the human “microbiome” plays an important role in
both health and disease. Bile acids function both as detergents molecules promoting …

The global emergence of multidrug-resistant Gram-negative bacteria is a growing threat to
antibiotic therapy. The chromosomally encoded drug efflux mechanisms that are ubiquitous …

Bacterial multidrug efflux pumps are antibiotic resistance determinants present in all
microorganisms. With few exceptions, they are chromosomally encoded and present a …

Bacterial multidrug efflux pumps have come to prominence in human and veterinary
pathogenesis because they help bacteria protect themselves against the antimicrobials …

The gut of warm-blooded animals is colonized by microbes possibly constituting at least 100
times more genetic material of microbial cells than that of the somatic cells of the host. These …