Could polygenic risk scores be useful in psychiatry?: a review

GK Murray, T Lin, J Austin, JJ McGrath, IB Hickie… - JAMA …, 2021 - jamanetwork.com
Importance Polygenic risk scores (PRS) are predictors of the genetic susceptibility to
diseases, calculated for individuals as weighted counts of thousands of risk variants in which …

Reviewing the genetics of heterogeneity in depression: operationalizations, manifestations and etiologies

N Cai, KW Choi, EI Fried - Human molecular genetics, 2020 - academic.oup.com
With progress in genome-wide association studies of depression, from identifying zero hits
in~ 16 000 individuals in 2013 to 223 hits in more than a million individuals in 2020 …

The emerging field of polygenic risk scores and perspective for use in clinical care

T Yanes, AM McInerney-Leo, MH Law… - Human molecular …, 2020 - academic.oup.com
Genetic testing is used widely for diagnostic, carrier and predictive testing in monogenic
diseases. Until recently, there were no genetic testing options available for multifactorial …

The role of Extrasynaptic GABA receptors in postpartum depression

YF Feng, YY Zhou, KM Duan - Molecular Neurobiology, 2024 - Springer
Postpartum depression is a serious disease with a high incidence and severe impact on
pregnant women and infants, but its mechanism remains unclear. Recent studies have …

The effect of digital mindfulness interventions on depressive, anxiety, and stress symptoms in pregnant women: A systematic review and meta-analysis

ML Mefrouche, EM Siegmann, S Böhme… - European Journal of …, 2023 - mdpi.com
Introduction. Pregnancy is a unique time in a woman's life that can be both exciting and
challenging. It is also a period that can be associated with significant stress, anxiety, and …

Perinatal depression is associated with a higher polygenic risk for major depressive disorder than non‐perinatal depression

J Kiewa, S Meltzer‐Brody, J Milgrom… - Depression and …, 2022 - Wiley Online Library
Background Distinctions between major depressive disorder (MDD) and perinatal
depression (PND) reflect varying views of PND, from a unique etiological subtype of MDD to …

Investigation of the interaction between Genetic Risk Score (GRS) and fatty acid quality indices on mental health among overweight and obese women

N Rasaei, M Samadi, A Khadem, SF Fatemi… - BMC Women's …, 2023 - Springer
Background & aims Mental disorders are associated with dietary fatty acids and genome-
wide association studies have found multiple risk loci robustly related to depression, anxiety …

Identification of women at high risk of postpartum psychiatric episodes: a population‐based study quantifying relative and absolute risks following exposure to selected …

BMW Johannsen, JT Larsen, X Liu… - Acta Psychiatrica …, 2024 - Wiley Online Library
Background We quantified relative and absolute risks of postpartum psychiatric episodes
(PPE) following risk factors: Young age, past personal or family history of psychiatric …

Early‐and late‐onset postpartum depression exhibit distinct associated factors: the IGEDEPP prospective cohort study

S Tebeka, Y Le Strat, L Mandelbrot… - … Journal of Obstetrics …, 2021 - Wiley Online Library
Objective To identify risk factors for early‐and late‐onset postpartum depression (PPD)
among a wide range of variables, including sociodemographic characteristics, childhood …

[HTML][HTML] Postpartum psychosis: Revisiting the phenomenology, nosology, and treatment

V Sharma, D Mazmanian, L Palagini… - Journal of Affective …, 2022 - Elsevier
Background To review the phenomenology, nosology, and treatment of postpartum
psychosis. Methods Using the keywords postpartum, puerperal, psychosis, bipolar, mania …