Type V protein secretion pathway: the autotransporter story
IR Henderson, F Navarro-Garcia… - Microbiology and …, 2004 - Am Soc Microbiol
Gram-negative bacteria possess an outer membrane layer which constrains uptake and
secretion of solutes and polypeptides. To overcome this barrier, bacteria have developed …
secretion of solutes and polypeptides. To overcome this barrier, bacteria have developed …
Microbial cell-surface display
Cell-surface display allows peptides and proteins to be displayed on the surface of microbial
cells by fusing them with the anchoring motifs. The protein to be displayed–the passenger …
cells by fusing them with the anchoring motifs. The protein to be displayed–the passenger …
Type V secretion: mechanism (s) of autotransport through the bacterial outer membrane
Autotransport in Gram-negative bacteria denotes the ability of surface-localized proteins to
cross the outer membrane (OM) autonomously. Autotransporters perform this task with the …
cross the outer membrane (OM) autonomously. Autotransporters perform this task with the …
The great escape: structure and function of the autotransporter proteins
IR Henderson, F Navarro-Garcia, JP Nataro - Trends in microbiology, 1998 - cell.com
The autotransporters, a family of secreted proteins from Gram-negative bacteria, possess an
overall unifying structure comprising three functional domains: the amino-terminal leader …
overall unifying structure comprising three functional domains: the amino-terminal leader …
From self sufficiency to dependence: mechanisms and factors important for autotransporter biogenesis
DL Leyton, AE Rossiter, IR Henderson - Nature Reviews Microbiology, 2012 - nature.com
Autotransporters are a superfamily of proteins that use the type V secretion pathway for their
delivery to the surface of Gram-negative bacteria. At first glance, autotransporters look to …
delivery to the surface of Gram-negative bacteria. At first glance, autotransporters look to …
Engineering a mouse metallothionein on the cell surface of Ralstonia eutropha CH34 for immobilization of heavy metals in soil
Here we describe targeting of the mouse metallothionein I (MT) protein to the cell surface of
the heavy metal-tolerant Ralstonia eutropha (formerly Alcaligenes eutrophus) CH34 strain …
the heavy metal-tolerant Ralstonia eutropha (formerly Alcaligenes eutrophus) CH34 strain …
Structure of the translocator domain of a bacterial autotransporter
CJ Oomen, P van Ulsen, P Van Gelder, M Feijen… - The EMBO …, 2004 - embopress.org
Autotransporters are virulence‐related proteins of Gram‐negative bacteria that are secreted
via an outer‐membrane‐based C‐terminal extension, the translocator domain. This domain …
via an outer‐membrane‐based C‐terminal extension, the translocator domain. This domain …
The autodisplay story, from discovery to biotechnical and biomedical applications
Among the pathways used by gram-negative bacteria for protein secretion, the
autotransporter pathway represents a solution of impressive simplicity. Proteins are …
autotransporter pathway represents a solution of impressive simplicity. Proteins are …
Autodisplay: one-component system for efficient surface display and release of soluble recombinant proteins from Escherichia coli
The immunoglobulin A protease family of secreted proteins are derived from self-
translocating polyprotein precursors which contain C-terminal domains promoting the …
translocating polyprotein precursors which contain C-terminal domains promoting the …
Protein engineering with bacterial display
PS Daugherty - Current opinion in structural biology, 2007 - Elsevier
Recent improvements in bacterial surface display systems coupled with efficient selection
and screening strategies are propelling bacterial display systems to the forefront of peptide …
and screening strategies are propelling bacterial display systems to the forefront of peptide …