OXA-48-like β-lactamases: global epidemiology, treatment options, and development pipeline

SE Boyd, A Holmes, R Peck… - Antimicrobial agents …, 2022 - Am Soc Microbiol
Modern medicine is threatened by the rising tide of antimicrobial resistance, especially
among Gram-negative bacteria, where resistance to β-lactams is most often mediated by β …

In vitro, in vivo and clinical studies comparing the efficacy of ceftazidime-avibactam monotherapy with ceftazidime-avibactam-containing combination regimens against carbapenem …

AT Aslan, Y Ezure, JP Horcajada, PNA Harris… - Frontiers in …, 2023 - frontiersin.org
Introduction Carbapenem-resistant Enterobacterales (CRE) and multidrug-resistant
Pseudomonas aeruginosa (MDR-PA) infections are associated with a high risk of morbidity …

Synergistic antibacterial effects of colistin in combination with aminoglycoside, carbapenems, cephalosporins, fluoroquinolones, tetracyclines, fosfomycin, and …

JC Ontong, NF Ozioma, SP Voravuthikunchai, S Chusri - Plos one, 2021 - journals.plos.org
Multidrug resistant Enterobacterales have become a serious global health problem, with
extended hospital stay and increased mortality. Antibiotic monotherapy has been reported …

Carbapenem-resistant hypermucoviscous Klebsiella pneumoniae clinical isolates from a tertiary hospital in China: Antimicrobial susceptibility, resistance phenotype …

Q Wang, M Chen, Q Ou, L Zheng, X Chen… - Frontiers in Cellular …, 2022 - frontiersin.org
Hypervirulent and multidrug-resistant Klebsiella pneumoniae poses a significant threat to
public health. We aimed to determine the common carbapenemase genotypes and the …

[PDF][PDF] 碳青霉烯类耐药革兰阴性菌联合药敏试验及报告专家共识

丁丽, 陈佰义, 李敏, 倪语星, 单斌, 苏丹虹… - 中国感染与化疗 …, 2023 - chinets.com
基金项目: 国家重点研发计划(2 0 2 1 YFC 2 7 0 1 8 0 0, 2021YFC2701803); 上海市2021
年度“科技创新行动计划” 抗菌新药药物敏感试验流行病学折点制定技术标准的建立 …

The place of new antibiotics for Gram-negative bacterial infections in intensive care: Report of a consensus conference

PF Dequin, C Aubron, H Faure, D Garot, M Guillot… - Annals of Intensive …, 2023 - Springer
Introduction New beta-lactams, associated or not with beta-lactamase inhibitors (NBs/BIs),
can respond to the spread of carbapenemase-producing enterobacteriales and …

Synergistic antibacterial activity of ceftazidime–avibactam in combination with colistin, gentamicin, amikacin, and fosfomycin against carbapenem-resistant Klebsiella …

NÜ Tüzemen, U Önal, O Merdan, B Akca, B Ener… - Scientific reports, 2024 - nature.com
Carbapenem-resistant Klebsiella pneumoniae (CPKP) infections seriously threaten global
public health. The main objective of this study was to assess the in-vitro synergistic activity of …

Ceftazidime/avibactam combined with colistin: a novel attempt to treat carbapenem-resistant Gram-negative bacilli infection

Z Zheng, Z Shao, L Lu, S Tang, K Shi, F Gong… - BMC Infectious …, 2023 - Springer
Background The rapid global emergence and spread of carbapenem-resistant Gram-
negative bacilli (CR-GNB) is recognized as a major public health concern, and there are …

[HTML][HTML] Clinical characteristics and outcomes of patients with multidrug-resistant Gram-negative bacterial infections treated with ceftazidime/avibactam

H Kuang, C Zhong, Y Wang, H Ye, K Ao, Z Zong… - Journal of global …, 2020 - Elsevier
Objectives The aim of present study was to investigate the clinical characteristics and
prognosis of patients with multidrug-resistant gram-negative bacterial (MDR-GNB) infections …

[HTML][HTML] Инфекции, вызванные карбапенеморезистентными энтеробактериями: эпидемиология, клиническое значение и возможности оптимизации …

СВ Яковлев, МП Суворова… - Антибиотики и …, 2020 - cyberleninka.ru
Устойчивость бактерий порядка Enterobacterales к карбапенемам может быть
реализована разными механизмами, но наиболее распространённый …