Tumor battlefield within inflamed, excluded or desert immune phenotypes: the mechanisms and strategies

S Zheng, W Wang, L Shen, Y Yao, W Xia… - … Hematology & Oncology, 2024 - Springer
The tumor microenvironment demonstrates great immunophenotypic heterogeneity, which
has been leveraged in traditional immune-hot/cold tumor categorization based on the …

Exploring the interaction between extracellular matrix components in a 3D organoid disease model to replicate the pathophysiology of breast cancer

A Bhattacharya, K Alam, NS Roy, K Kaur… - Journal of Experimental …, 2023 - Springer
In vitro models are necessary to study the pathophysiology of the disease and the
development of effective, tailored treatment methods owing to the complexity and …

Tumor Organoids: The Era of Personalized Medicine

NV Rassomakhina, AY Ryazanova, AR Likhov… - Biochemistry …, 2024 - Springer
The strategies of future medicine are aimed to modernize and integrate quality approaches
including early molecular-genetic profiling, identification of new therapeutic targets and …

Degranulation assay to evaluate NK cell natural and antibody-dependent cell-mediated cytotoxicity against A549 tumor spheroids

A Lopez-Pardo, A Amarilla-Irusta… - Methods in cell …, 2024 - pubmed.ncbi.nlm.nih.gov
Adoptive natural killer (NK) cell-based immunotherapy is a promising treatment approach in
cancer that is showing notable efficacy against hematological malignancies. However, the …