Defining IL‐6 levels in healthy individuals: A meta‐analysis

EA Said, I Al‐Reesi, N Al‐Shizawi, S Jaju… - Journal of medical …, 2021 - Wiley Online Library
Abstract Background Interleukin‐6 (IL‐6) is produced by and impacts different cell types in
human. IL‐6 is associated with different diseases and viral infections, including COVID‐19 …

[HTML][HTML] Age and genotype dependent erythropoietin protection in COVID-19

KI Papadopoulos, W Sutheesophon… - World Journal of Stem …, 2021 - ncbi.nlm.nih.gov
Erythropoietin (EPO) is the main mediator of erythropoiesis and an important tissue
protective hormone that appears to mediate an ancestral neuroprotective innate immune …

[HTML][HTML] Deleterious effect of angiotensin-converting enzyme gene polymorphism in vitiligo patients

NS Basher, A Malik, F Aldakheel, AA Chaudhary… - Saudi Journal of …, 2021 - Elsevier
Vitiligo is a rare skin condition caused by an immune reaction. Vitiligo can occur anywhere
on the body. This proposed explanation of vitiligo makes it clear that vitiligo is not linked to …

The Renin-Angiotensin System: The Challenge behind Autoimmune Dermatological Diseases

MA Maranduca, MA Cosovanu, A Clim, AC Pinzariu… - Diagnostics, 2023 - mdpi.com
Autoimmune dermatological diseases (AIDD) encompass a diverse group of disorders
characterized by aberrant immune responses targeting the skin and its associated …

[HTML][HTML] Therapeutic effects of iNOS inhibition against vitiligo in an animal model

H Mansourpour, K Ziari, SK Motamedi… - European Journal of …, 2019 - ncbi.nlm.nih.gov
Nitric oxide (NO) is involved in several biological processes, but its role in human
melanogenesis and vitiligo need further studies. Previous studies revealed that exposure to …

Inducible nitric oxide synthase iNOS-954-G> C and Ex16+ 14-C> T gene polymorphisms and susceptibility to vitiligo in the Saudi population

F Al-Harthi, GB Huraib, M Mustafa… - Pharmacogenomics …, 2022 - Taylor & Francis
Objective Vitiligo is an acquired pigmentary skin disorder with regional disappearance of
melanocytes. Multigenic inheritance has been proposed in the pathogenesis of vitiligo. The …

Involvement of different genes expressions during immunological and inflammatory responses in vitiligo

CK Sharma, M Sharma, K Prasad - Critical Reviews™ in …, 2017 - dl.begellhouse.com
Vitiligo is a condition of the skin distinguished by hypo-pigmentation. Etiology of this disorder
is unknown, and several theories and mechanisms have been hypothesized. The …

[HTML][HTML] Associations of angiotensin-converting enzyme gene insertion/deletion (ACE Gene I/D) polymorphism with vitiligo: an updated systematic review and meta …

M Almohideb - Cureus, 2020 - ncbi.nlm.nih.gov
Objective The objective of the article is to summarize the current evidence regarding the
association between angiotensin-converting enzyme insertion/deletion (ACE I/D) gene …

The immunogenetics of vitiligo: An approach toward revealing the secret of depigmentation

M Dwivedi, NC Laddha, R Begum - The Immunogenetics of Dermatologic …, 2022 - Springer
Vitiligo is a hypomelanotic skin disease and considered to be of autoimmune origin due to
breaching of immunological self-tolerance, resulting in inappropriate immune responses …

Vitiligo: From mechanisms of disease to treatable pathways

GN Pathak, IJ Tan, G Bai, J Dhillon… - Skin Health and …, 2024 - Wiley Online Library
Vitiligo is a chronic autoimmune‐mediated disease characterised by the loss of pigmentary
melanocytes in the epidermis. Vitiligo is associated with loss of functional epithelium and …