Pathogenicity and virulence of human respiratory syncytial virus: Multifunctional nonstructural proteins NS1 and NS2
TN Merritt, J Pei, DW Leung - Virulence, 2023 - Taylor & Francis
Human respiratory syncytial virus (hRSV) is a major cause of acute lower respiratory tract
infections in children under the age of two as well as in the elderly and …
infections in children under the age of two as well as in the elderly and …
An RSV live-attenuated vaccine candidate lacking G protein mucin domains is attenuated, immunogenic, and effective in preventing RSV in BALB/c mice
MK Roe, MA Perez, HM Hsiao, SA Lapp… - The Journal of …, 2023 - academic.oup.com
Background Respiratory syncytial virus (RSV) is a leading viral respiratory pathogen in
infants. The objective of this study was to generate RSV live-attenuated vaccine (LAV) …
infants. The objective of this study was to generate RSV live-attenuated vaccine (LAV) …
A ligation and restriction enzyme independent cloning technique: an alternative to conventional methods for cloning hard-to-clone gene segments in the influenza …
Background Reverse genetics is used in many laboratories around the world and enables
the creation of tailor-made influenza viruses with a desired genotype or phenotype …
the creation of tailor-made influenza viruses with a desired genotype or phenotype …
[PDF][PDF] 病毒重组细菌人工染色体构建, 突变及应用
刘立涛， 孙洪磊， 刘金华 - 生命科学, 2017 - lifescience.sinh.ac.cn
如何快速, 方便地保存和修饰基因组较大的DNA 和RNA 病毒核酸一直是病毒学研究的重点.
细菌人工染色体(bacterial artificial chromosome, BAC) 为解决这两个问题提供了便利 …
细菌人工染色体(bacterial artificial chromosome, BAC) 为解决这两个问题提供了便利 …
Recombinant RSV with silent mutations, vaccines, and methods related thereto
ML Moore, M Jia, A Hotard, E Littauer… - US Patent …, 2020 - Google Patents
In certain embodiments, the disclosure relates to the polynucleotide sequences of
respiratory syncytial virus (RSV). In certain embodiments, the disclosure relates to isolated …
respiratory syncytial virus (RSV). In certain embodiments, the disclosure relates to isolated …
Chimeric RSV, immunogenic compositions, and methods of use
ML Moore, C Rostad - US Patent 11,235,050, 2022 - Google Patents
This disclosure relates to chimeric respiratory syncytial virus (RSV), live attenuated vaccine
and immunogenic compositions, and methods of use. In certain embodiments, the chimeric …
and immunogenic compositions, and methods of use. In certain embodiments, the chimeric …
Recombinant RSV with silent mutations, vaccines, and methods related thereto
ML Moore, M Jia, A Hotard, E Littauer… - US Patent …, 2022 - Google Patents
In certain embodiments, the disclosure relates to the polynucleotide sequences of
respiratory syncytial virus (RSV). In certain embodiments, the disclosure relates to isolated …
respiratory syncytial virus (RSV). In certain embodiments, the disclosure relates to isolated …
Recombinant rsv with silent mutations, vaccines, and methods related thereto
ML Moore, M Jia, A Hotard, E Littauer… - US Patent App. 18 …, 2023 - Google Patents
In certain embodiments, the disclosure relates to the polynucleotide sequences of
respiratory syncytial virus (RSV). In certain embodiments, the disclosure relates to isolated …
respiratory syncytial virus (RSV). In certain embodiments, the disclosure relates to isolated …