A comprehensive investigation of hydrazide and its derived structures in the agricultural fungicidal field

J Chang, Y Liu, T Zhang, Z Chen… - Journal of Agricultural …, 2023 - ACS Publications
Hydrazides are present in many bioactive molecules and exhibit a variety of biological
activities, such as insecticidal, herbicidal, antifungal, antitumor, and antiviral effects. In this …

Discovery of novel quinazoline-2-aminothiazole hybrids containing a 4-piperidinylamide linker as potential fungicides against the phytopathogenic fungus Rhizoctonia …

M Ding, N Wu, Q Lin, Y Yan, Y Yang… - Journal of Agricultural …, 2022 - ACS Publications
A total of 29 novel quinazoline-2-aminothiazole hybrids containing a 4-piperidinylamide
linker were designed, synthesized, and evaluated for their anti-microbial properties against …

Design, synthesis, and biological activity of novel fungicides containing a 1, 2, 3, 4-tetrahydroquinoline scaffold and acting as laccase inhibitors

X Zhang, H Xu, H Su, X Yang, T Sun, X Lu… - Journal of Agricultural …, 2022 - ACS Publications
Laccase is a novel target for fungicides. We previously developed a new fungicide, 4-
chlorocinnamaldehyde thiosemicarbazide (PMDD-5Y), as a laccase inhibitor. The …

Synthesis, antifungal activity, and 3D-QASR of novel 1, 2, 3, 4-tetrahydroquinoline derivatives containing a pyrimidine ether scaffold as chitin synthase inhibitors

X Zhang, Z Yang, H Xu, Y Liu, X Yang… - Journal of Agricultural …, 2022 - ACS Publications
The introduction of active groups of natural products into the framework of pesticide
molecules is an effective approach for discovering active lead compounds, and thus has …

Discovery of novel pyrazole carboxylate derivatives containing thiazole as potential fungicides

D Xia, X Cheng, X Liu, C Zhang, Y Wang… - Journal of Agricultural …, 2021 - ACS Publications
Inspired by commercially established fluxapyroxad as the lead compound of novel efficient
antifungal ingredients, novel pyrazole carboxylate derivatives containing a flexible thiazole …

Synthesis, Structural Characterization, and Antibacterial and Antifungal Activities of Novel 1,2,4-Triazole Thioether and Thiazolo[3,2-b]-1,2,4-triazole Derivatives …

M Ding, S Wan, N Wu, Y Yan, J Li… - Journal of Agricultural and …, 2021 - ACS Publications
A total of 52 novel 1, 2, 4-triazole thioether and thiazolo [3, 2-b]-1, 2, 4-triazole derivatives
bearing the 6-fluoroquinazolinyl moiety were designed, synthesized, and evaluated as …

Design, synthesis, and structure–activity relationship of quinazolinone derivatives as potential fungicides

JW Peng, XD Yin, H Li, KY Ma, ZJ Zhang… - Journal of Agricultural …, 2021 - ACS Publications
Plant diseases caused by phytopathogenic fungi reduce the yield and quality of crops. To
develop novel antifungal agents, we designed and synthesized eight series of …

Design, synthesis, cytotoxic activities, and molecular docking of chalcone hybrids bearing 8-hydroxyquinoline moiety with dual tubulin/EGFR kinase inhibition

MM Amin, GEDA Abuo-Rahma, MSA Shaykoon… - Bioorganic …, 2023 - Elsevier
The present study established thirteen novel 8-hydroxyquinoline/chalcone hybrids 3a–m of
hopeful anticancer activity. According to NCI screening and MTT assay results, compounds …

Novel citral-thiazolyl hydrazine derivatives as promising antifungal agents against phytopathogenic fungi

L Zhang, Y Shi, X Duan, W He, H Si… - Journal of Agricultural …, 2021 - ACS Publications
To develop new antifungal agents against phytopathogenic fungi, a series of citral-thiazolyl
hydrazine derivatives were designed, synthesized, and characterized by FT-IR, 1H NMR …

Venturicidin A Is a Potential Fungicide for Controlling Fusarium Head Blight by Affecting Deoxynivalenol Biosynthesis, Toxisome Formation, and Mitochondrial …

L Hu, C Guo, J Chen, R Jia, Y Sun, S Cao… - Journal of Agricultural …, 2023 - ACS Publications
Fusarium graminearum, which causes Fusarium head blight (FHB) in cereals, is one of the
most devastating fungal diseases by causing great yield losses and mycotoxin …