Enhanced expression of chemotactic cytokines (aka chemokines) within pancreatic islets
likely contributes to islet inflammation by regulating the recruitment and activation of various …

The mechanisms of impaired glucose-induced insulin secretion from the pancreatic β-cells
in obesity have not yet been completely elucidated. Here, we aimed to assess the effects of …

Islet transplant is a curative treatment for insulin-dependent diabetes. However, challenges,
including poor tissue survival and a lack of efficient engraftment, must be overcome. An …

Steroid-induced diabetes is the most common form of drug-induced hyperglycemia.
Therefore, metabolic and immunological alterations associated with chronic oral …

Glucocorticoids (GCs) act through the glucocorticoid receptor (GR) and are commonly used
as anti-inflammatory and immunosuppressant medications. Chronic GC use has been linked …

Introduction: Shuanghuanglian injection (lyophilized)(SHLI) is commonly used to treat
respiratory tract infection. Shenmai injection (SMI) is mainly used to treat cardiovascular …

Glucocorticoids (GCs) are heavily prescribed to control inflammation in various human
diseases; however, side effects associated with GCs are well documented and lead to …

Glucocorticoids (GCs) are widely used in medicine for their role in the treatment of
autoimmune-mediated conditions, certain cancers, and organ transplantation. The …

We previously reported that N-adamantyl-4-methylthiazol-2-amine (KHG26693) suppresses
amyloid beta (Aβ)-induced neuronal oxidative damage in cortical neurons. Here we …

Glucocorticoids are clinically essential drugs used routinely to control inflammation.
However, a host of metabolic side effects manifests upon usage beyond a few days. In the …