Red blood cells (RBCs) release extracellular vesicles (EVs) including both endosome-
derived exosomes and plasma-membrane-derived microvesicles (MVs). RBC-derived EVs …

The diversity of platelet microparticles : Current Opinion in Hematology The diversity of platelet
microparticles : Current Opinion in Hematology Log in or Register Subscribe to journalSubscribe …

Sickle cell disease (SCD) is a hypercoagulable state. Patients exhibit increased platelet
activation, high plasma levels of markers of thrombin generation, depletion of natural …

Chronic hemolysis, enhanced oxidative stress, and decreased nitric oxide (NO)
bioavailability promote vasculopathy in sickle cell anemia (SCA). Oxidative stress and NO …

Long noncoding RNAs (lncRNAs) are not transcriptional noise, as previously understood,
but are currently considered to be multifunctional. Exosomes are derived from the internal …

Blood from patients with sickle cell disease contains microparticles (MP) derived from
multiple cell sources, including red cells, platelets, monocytes and endothelial cells. MP s …

Sickle cell disease (SCD) is a hematologic disorder caused by a well‐characterized point
mutation in the β‐globin gene. Abnormal polymerization of hemoglobin tetramers results in …

Chronic activation of coagulation is one of the features of sickle cell disease (SCD).
Increased tissue factor expression, phosphatidylserine exposure, thrombin generation and …

Introduction Circulating microparticles (MP) have been described in sickle cell anaemia
(SCA); however, their interaction with endothelial markers remains unclear. We investigated …

Prototype of monogenic disorder, sickle cell disease (SCD) is caused by a unique single
mutation in the β-globin gene, leading to the production of the abnormal hemoglobin S …