Assessing the clinical severity of the Omicron variant in the Western Cape Province, South Africa, using the diagnostic PCR proxy marker of RdRp target delay to …

H Hussey, MA Davies, A Heekes, C Williamson… - International Journal of …, 2022 - Elsevier
Background At present, it is unclear whether the extent of reduced risk of severe disease
seen with SARS-Cov-2 Omicron variant infection is caused by a decrease in variant …

How South Africa used national cycle threshold (ct) values to continuously monitor SARS-CoV-2 laboratory test quality

LE Scott, N Hsiao, G Dor, L Hans, P Marokane… - Diagnostics, 2023 - mdpi.com
The high demand for SARS-CoV-2 tests but limited supply to South African laboratories
early in the COVID-19 pandemic resulted in a heterogenous diagnostic footprint of open and …

Higher mortality associated with the SARS-CoV-2 Delta variant in the Western Cape, South Africa, using RdRp target delay as a proxy

H Hussey, MA Davies, A Heekes, C Williamson… - MedRxiv, 2021 - medrxiv.org
A novel proxy for the Delta variant, RNA-dependent RNA polymerase target delay in the
Seegene Allplex™ 2019-nCoV PCR assay, was associated with higher mortality (adjusted …