Role of myeloid cells in ischemic retinopathies: recent advances and unanswered questions

RA Shahror, CA Morris, AA Mohammed, M Wild… - Journal of …, 2024 - Springer
Myeloid cells including microglia and macrophages play crucial roles in retinal homeostasis
by clearing cellular debris and regulating inflammation. These cells are activated in several …

Microglia in retinal angiogenesis and diabetic retinopathy

A Hu, MHH Schmidt, N Heinig - Angiogenesis, 2024 - Springer
Diabetic retinopathy has a high probability of causing visual impairment or blindness
throughout the disease progression and is characterized by the growth of new blood vessels …

Correlation between diabetic retinopathy and diabetic nephropathy: a two-sample Mendelian randomization study

J Fang, C Luo, D Zhang, Q He, L Liu - Frontiers in Endocrinology, 2023 - frontiersin.org
Rationale & objective A causal relationship concerning diabetic retinopathy (DR) and
diabetic nephropathy (DN) has been studied in many epidemiological observational studies …

Calbindin 2-specific deletion of arginase 2 preserves visual function after optic nerve crush

SAH Zaidi, Z Xu, T Lemtalsi, P Sandow, S Athota… - Cell Death & …, 2023 - nature.com
We previously found that global deletion of the mitochondrial enzyme arginase 2 (A2) limits
optic nerve crush (ONC)-induced neuronal death. Herein, we examined the cell-specific role …

Spermine oxidase inhibitor, MDL 72527, reduced neovascularization, vascular permeability, and acrolein-conjugated proteins in a mouse model of ischemic …

A Alhumaid, F Liu, S Shan, E Jafari, N Nourin… - Tissue …, 2024 - Taylor & Francis
Disruptions in polyamine metabolism have been identified as contributing factors to various
central nervous system disorders. Our laboratory has previously highlighted the crucial role …

[HTML][HTML] Multi-color flow cytometry protocol to characterize myeloid cells in mouse retina research

W Xiao, RA Shahror, CA Morris, RB Caldwell… - Bio …, 2023 - ncbi.nlm.nih.gov
Myeloid cells, specifically microglia and macrophages, are activated in retinal diseases and
can improve or worsen retinopathy outcomes based on their inflammatory phenotype …

[HTML][HTML] Human umbilical cord mesenchymal stem cells derived-exosomes on VEGF-A in hypoxic-induced mice retinal astrocytes and mice model of retinopathy of …

XT Zhang, BW Zhao, YL Zhang… - International Journal of …, 2024 - ncbi.nlm.nih.gov
AIM To observe the effect of human umbilical cord mesenchymal stem cells (hUCMSCs)
secretions on the relevant factors in mouse retinal astrocytes, and to investigate the effect of …

Role of acyl-coenzyme A: cholesterol transferase 1 (ACAT1) in retinal neovascularization

SAH Zaidi, T Lemtalsi, Z Xu, I Santana… - Journal of …, 2023 - Springer
Background We have investigated the efficacy of a new strategy to limit pathological retinal
neovascularization (RNV) during ischemic retinopathy by targeting the cholesterol …

[HTML][HTML] Triciribine attenuates pathological neovascularization and vascular permeability in a mouse model of proliferative retinopathy

S Shan, F Liu, E Ford, RB Caldwell… - Biomedicine & …, 2023 - Elsevier
Proliferative retinopathies are the leading cause of irreversible blindness in all ages, and
there is a critical need to identify novel therapies. We investigated the impact of triciribine …

[PDF][PDF] Патогенетична та діагностична значимість генетичного дефіциту фолатного циклу в розвитку діабетичної ретинопатії у хворих на цукровий діабет 2 …

ЮВ Прокопенко - 2024 - ir.librarynmu.com
Національний медичний університет імені ООБогомольця Міністерств Page 1
Національний медичний університет імені ООБогомольця Міністерство охорони …