MOG-IgG-associated optic neuritis, encephalitis, and myelitis: lessons learned from neuromyelitis optica spectrum disorder

GR Dos Passos, LM Oliveira, BK Da Costa… - Frontiers in …, 2018 - frontiersin.org
Antibodies against myelin oligodendrocyte glycoprotein (MOG-IgG) have been found in
some cases diagnosed as seronegative neuromyelitis optica spectrum disorder (NMOSD) …

Atypical inflammatory demyelinating syndromes of the CNS

TA Hardy, SW Reddel, MH Barnett, J Palace… - The Lancet …, 2016 - thelancet.com
Atypical inflammatory demyelinating syndromes are rare disorders that differ from multiple
sclerosis owing to unusual clinical or MRI findings or poor response to treatments used for …

Body fluid biomarkers for multiple sclerosis—the long road to clinical application

CE Teunissen, A Malekzadeh, C Leurs… - Nature Reviews …, 2015 - nature.com
There is a strong unmet clinical need for objective body fluid biomarkers to assist early
diagnosis and estimate long-term prognosis, monitor treatment response and predict …

Effectiveness of mycophenolate mofetil as first-line therapy in AQP4-IgG, MOG-IgG, and seronegative neuromyelitis optica spectrum disorders

A Montcuquet, N Collongues, C Papeix… - Multiple Sclerosis …, 2017 - journals.sagepub.com
Objective: To evaluate the effectiveness and tolerance of mycophenolate mofetil (MMF) as a
first-line treatment in neuromyelitis optica spectrum disorder (NMOSD). Methods: In all, 67 …

Neuromyelitis optica spectrum disorders: comparison of clinical and magnetic resonance imaging characteristics of AQP4‐IgG versus MOG‐IgG seropositive cases in …

ED Van Pelt, YYM Wong, IA Ketelslegers… - European journal of …, 2016 - Wiley Online Library
Background and purpose Neuromyelitis optica spectrum disorders (NMOSDs) are a group of
rare inflammatory demyelinating disorders of the central nervous system. The identification …

MOG-antibody associated demyelinating disease of the CNS: a clinical and pathological study in Chinese Han patients

L Zhou, Y Huang, H Li, J Fan, J Zhangbao, H Yu… - Journal of …, 2017 - Elsevier
We aim to evaluate the clinical relevance of MOG-ab in a cohort of Chinese Han adults with
CNS inflammatory demyelinating diseases (IDDs). MOG-ab and AQP4-ab were examined …

Review of approved NMO therapies based on mechanism of action, efficacy and long-term effects

SA Brod - Multiple Sclerosis and Related Disorders, 2020 - Elsevier
Importance Neuromyelitis optica (NMO-including NMO spectrum disorders [NMOSD]) is a
devastating disease. Eighty-three percent of patients with transverse myelitic (TM) attacks …

Pharmacotherapy for neuromyelitis optica spectrum disorders: current management and future options

N Collongues, E Ayme-Dietrich, L Monassier… - Drugs, 2019 - Springer
Neuromyelitis optica (NMO) is an inflammatory and demyelinating disease of the central
nervous system. Although the prevalence of NMO is low, the rapid and severe impairment …

Finding NMO: the evolving diagnostic criteria of neuromyelitis optica

JL Bennett - Journal of Neuro-Ophthalmology, 2016 - journals.lww.com
Neuromyelitis optica (NMO) is an autoimmune demyelinating disorder of the central nervous
system (CNS) with predilection for the optic nerves and spinal cord. Since its emergence in …

Demyelinating diseases in Asia

H Ochi, K Fujihara - Current Opinion in neurology, 2016 - journals.lww.com
MS prevalence has been low but is increasing in Asia. In contrast, NMO/NMOSD prevalence
seems relatively constant in the world. Asian MS is not fundamentally different from Western …