The interplay between kinetics and thermodynamics in furan diels–alder chemistry for sustainable chemicals production

RC Cioc, M Crockatt, JC van der Waal… - Angewandte Chemie …, 2022 - Wiley Online Library
Biomass‐derived furanic platform molecules have emerged as promising building blocks for
renewable chemicals and functional materials. To this aim, the Diels–Alder (DA) …

Biobased C6-Furans in Organic Synthesis and Industry: Cycloaddition Chemistry as a Key Approach to Aromatic Building Blocks

FA Kucherov, LV Romashov… - ACS Sustainable …, 2021 - ACS Publications
Rapid development in the area of cellulose biomass conversion to furanic platform
chemicals has led to expectations of their valuable practical use. Impressive research …

Discovery of 2-[1-(4,4-Difluorocyclohexyl)piperidin-4-yl]-6-fluoro-3-oxo-2,3-dihydro-1H-isoindole-4-carboxamide (NMS-P118): A Potent, Orally Available, and Highly …

G Papeo, H Posteri, D Borghi, AA Busel… - Journal of medicinal …, 2015 - ACS Publications
The nuclear protein poly (ADP-ribose) polymerase-1 (PARP-1) has a well-established role
in the signaling and repair of DNA and is a prominent target in oncology, as testified by the …

Self-healing Polymers (SHPs) via Reversible Deactivation Radical Polymerization (RDRP): Syntheses, Property and Applications.

J Rawat, AK Yadav, NB Pramanik - Polymer, 2024 - Elsevier
Self-healing polymeric materials are intelligent materials engineered to autonomously repair
damages using external stimuli which are the vanguard of sustainable materials research …

Polymeric Antioxidant via ROMP of Bioderived Tricyclic Oxanorbornene Based on Vanillin and Furfurylamine

M Naguib, MA Yassin - ACS Applied Polymer Materials, 2022 - ACS Publications
Herein, a bioderived antioxidant oxanorbornene lactam monomer bearing a vanillyl moiety
has been successfully synthesized. The monomer was synthesized via reductive amination …

Systematic Study of Aromatic‐Ring‐Targeted Cycloadditions of 5‐Hydroxymethylfurfural Platform Chemicals

GM Averochkin, EG Gordeev… - …, 2021 - Wiley Online Library
The reaction space of the furanics‐to‐aromatics (F2A) conversion process for 5‐
hydroxymethylfurfural (HMF)‐based platform chemicals has been explored both …

Rapid access to molecular complexity from bioderived 5-HMF derivatives via cascade cycloadditions

GM Averochkin, EG Gordeev, FA Kucherov… - Green …, 2023 - pubs.rsc.org
For the first time, the transformation of biobased 5-HMF derivatives succeeded in a 2×[4+ 2]
cascade cycloaddition reaction, leading to a drastic (3–5-fold) increase in molecular …

New class of hantaan virus inhibitors based on conjugation of the isoindole fragment to (+)-camphor or (−)-fenchone hydrazonesv

OI Yarovaya, KS Kovaleva, AA Zaykovskaya… - Bioorganic & Medicinal …, 2021 - Elsevier
This work presents the design and synthesis of camphor, fenchone, and norcamphor N-
acylhydrazone derivatives as a new class of inhibitors of the Hantaan virus, which causes …

Rapid Ring‐Opening Metathesis Polymerization of Monomers Obtained from Biomass‐Derived Furfuryl Amines and Maleic Anhydride

A Blanpain, JH Clark, TJ Farmer, Y Guo… - …, 2019 - Wiley Online Library
Well‐controlled and extremely rapid ring‐opening metathesis polymerization of unusual
oxanorbornene lactam esters by Grubbs third‐generation catalyst is used to prepare a range …

Continuous-flow catalytic hydrogenation of 3a, 6-epoxyisoindoles

VP Zaytsev, FI Zubkov, DF Mertsalov, DN Orlova… - Russian Chemical …, 2015 - Springer
Abstract Selective catalytic (10% Pd/C) hydrogenation of the double bond in the oxabicyclo
[2.2. 1] heptene fragment of substituted fused 1-oxo-3a, 6-epoxyisoindoles is described. A …