Bleeding and thrombotic complications in the use of extracorporeal membrane oxygenation

J Thomas, V Kostousov, J Teruya - Seminars in thrombosis and …, 2018 - thieme-connect.com
Extracorporeal membrane oxygenation (ECMO) has been used for> 40 years to support
lung and heart failure; however, bleeding and thrombosis remain serious complications. The …

Current understanding of how extracorporeal membrane oxygenators activate haemostasis and other blood components

AJ Doyle, BJ Hunt - Frontiers in medicine, 2018 - frontiersin.org
Extracorporeal membrane oxygenators are used in critical care for the management of
severe respiratory and cardiac failure. Activation of the coagulation system is initiated by the …

2021 ELSO adult and pediatric anticoagulation guidelines

ABV McMichael, LM Ryerson, D Ratano, E Fan… - ASAIO …, 2022 - journals.lww.com
Disclaimer: These guidelines for adult and pediatric anticoagulation for extracorporeal
membrane oxygenation are intended for educational use to build the knowledge of …

[HTML][HTML] Iron in the tumor microenvironment—connecting the dots

C Pfeifhofer-Obermair, P Tymoszuk, V Petzer… - Frontiers in …, 2018 - frontiersin.org
Iron metabolism and tumor biology are intimately linked. Iron facilitates the production of
oxygen radicals, which may either result in iron-induced cell death, ferroptosis, or contribute …

Liquid flow and control without solid walls

P Dunne, T Adachi, AA Dev, A Sorrenti, L Giacchetti… - Nature, 2020 - nature.com
When miniaturizing fluidic circuitry, the solid walls of the fluid channels become increasingly
important because they limit the flow rates achievable for a given pressure drop, and they …

The quest for blood-compatible materials: Recent advances and future technologies

M Hedayati, MJ Neufeld, MM Reynolds… - Materials Science and …, 2019 - Elsevier
The development of blood-compatible materials represents a grand challenge in
biomaterials science. Blood is a complex fluid containing many types of living cells …

Therapeutic Modulation of the Host Defense by Hemoadsorption with CytoSorb®—Basics, Indications and Perspectives—A Scoping Review

T Koehler, E Schwier, J Praxenthaler… - International Journal of …, 2021 - mdpi.com
The “normal” immune response to an insult triggers a highly regulated response determined
by the interaction of various immunocompetent cells with pro-and anti-inflammatory …

Modeling and prediction of flow-induced hemolysis: a review

MM Faghih, MK Sharp - Biomechanics and modeling in mechanobiology, 2019 - Springer
Despite decades of research related to hemolysis, the accuracy of prediction algorithms for
complex flows leaves much to be desired. Fundamental questions remain about how …

Neurocritical care for extracorporeal membrane oxygenation patients

SM Cho, S Farrokh, G Whitman, TP Bleck… - Critical care …, 2019 - journals.lww.com
Objectives: To review the neurocritical care aspects of patients supported by extracorporeal
membrane oxygenation, including cerebral physiology, neurologic monitoring, use of …

Hemolysis at low blood flow rates: in-vitro and in-silico evaluation of a centrifugal blood pump

M Schöps, SH Groß-Hardt, T Schmitz-Rode… - Journal of translational …, 2021 - Springer
Background Treating severe forms of the acute respiratory distress syndrome and cardiac
failure, extracorporeal membrane oxygenation (ECMO) has become an established …