Lactoferrin's anti-cancer properties: Safety, selectivity, and wide range of action

A Cutone, L Rosa, G Ianiro, MS Lepanto… - Biomolecules, 2020 - mdpi.com
Despite recent advances in cancer therapy, current treatments, including radiotherapy,
chemotherapy, and immunotherapy, although beneficial, present attendant side effects and …

Lactoferrin as protective natural barrier of respiratory and intestinal mucosa against coronavirus infection and inflammation

E Campione, T Cosio, L Rosa, C Lanna… - International Journal of …, 2020 - mdpi.com
Recently, the world has been dealing with a devastating global pandemic coronavirus
infection, with more than 12 million infected worldwide and over 300,000 deaths as of May …

Lactoferrin: An overview of its main functions, immunomodulatory and antimicrobial role, and clinical significance

M Sienkiewicz, A Jaśkiewicz, A Tarasiuk… - Critical reviews in food …, 2022 - Taylor & Francis
Lactoferrin (LF), a glycoprotein found in mucosal secretions, is characterized by a wide
range of functions, including immunomodulatory and anti-inflammatory activities. Moreover …

Lactoferrin in aseptic and septic inflammation

MS Lepanto, L Rosa, R Paesano, P Valenti, A Cutone - Molecules, 2019 - mdpi.com
Lactoferrin (Lf), a cationic glycoprotein able to chelate two ferric irons per molecule, is
synthesized by exocrine glands and neutrophils. Since the first anti-microbial function …

Lactoferrin as antiviral treatment in COVID-19 management: preliminary evidence

E Campione, C Lanna, T Cosio, L Rosa… - International journal of …, 2021 - mdpi.com
Lactoferrin (Lf), a multifunctional cationic glycoprotein synthesized by exocrine glands and
neutrophils, possesses an in vitro antiviral activity against SARS-CoV-2. Thus, we conducted …

Ambulatory COVID-19 patients treated with lactoferrin as a supplementary antiviral agent: A preliminary study

L Rosa, G Tripepi, E Naldi, M Aimati… - Journal of clinical …, 2021 - mdpi.com
SARS-CoV-2, an enveloped, single-stranded RNA virus causing COVID-19, exerts morbidity
and mortality especially in elderly, obese individuals and those suffering from chronic …

Insights into the research trends on bovine colostrum: Beneficial health perspectives with special reference to manufacturing of functional foods and feed supplements

R Mehra, R Garhwal, K Sangwan, RPF Guiné… - Nutrients, 2022 - mdpi.com
Bovine colostrum (BC) is the initial mammary secretion after parturition, which is nature's
bountiful source consisting of nutritional and bioactive components present in a highly …

The functional role of lactoferrin in intestine mucosal immune system and inflammatory bowel disease

N Liu, G Feng, X Zhang, Q Hu, S Sun, J Sun… - Frontiers in …, 2021 - frontiersin.org
Inflammatory bowel disease (IBD), encompassing ulcerative colitis (UC) and Crohn's
disease (CD), is one of the main types of intestinal inflammatory diseases with intestine …

Nutrition in chronic inflammatory conditions: bypassing the mucosal block for micronutrients

F Roth‐Walter, R Berni Canani, L O'Mahony, D Peroni… - Allergy, 2024 - Wiley Online Library
Nutritional Immunity is one of the most ancient innate immune responses, during which the
body can restrict nutrients availability to pathogens and restricts their uptake by the gut …

Lactoferrin for iron-deficiency anemia in children with inflammatory bowel disease: a clinical trial

D El Amrousy, D El-Afify, A Elsawy, M Elsheikh… - Pediatric …, 2022 - nature.com
Background Iron-deficiency anemia (IDA) is common in children with inflammatory bowel
disease (IBD); however, oral iron supplements are commonly associated with poor …