Hypoxia in prostate cancer: a powerful shield against tumour destruction?

L Marignol, M Coffey, M Lawler, D Hollywood - Cancer treatment reviews, 2008 - Elsevier
Tumour hypoxia is progressively emerging as a common feature of prostate tumours
associated with poor prognosis. While the molecular basis of disease progression is …

Escalated-dose versus standard-dose conformal radiotherapy in prostate cancer: first results from the MRC RT01 randomised controlled trial

DP Dearnaley, MR Sydes, JD Graham, EG Aird… - The lancet …, 2007 - thelancet.com
Background In men with localised prostate cancer, conformal radiotherapy (CFRT) could
deliver higher doses of radiation than does standard-dose conventional radical external …

Magnetic resonance imaging (MRI) anatomy of the prostate and application of MRI in radiotherapy planning

GM Villeirs, GO De Meerleer - European journal of radiology, 2007 - Elsevier
Radiotherapy planning for prostate carcinoma has traditionally been performed on
computed tomography (CT)-images, on which both the high dose areas (prostate with or …

Combined Use of Diffusion-Weighted MRI and 1H MR Spectroscopy to Increase Accuracy in Prostate Cancer Detection

SA Reinsberg, GS Payne, SF Riches… - American Journal of …, 2007 - Am Roentgen Ray Soc
OBJECTIVE. The objective of our study was to establish the sensitivity and specificity for
prostate cancer detection using a combined 1H MR spectroscopy and diffusion-weighted …

Diffusion‐weighted imaging of the prostate and rectal wall: comparison of biexponential and monoexponential modelled diffusion and associated perfusion …

SF Riches, K Hawtin… - NMR in Biomedicine …, 2009 - Wiley Online Library
This study compares parameters from monoexponential and biexponential modelling of
diffusion‐weighted imaging of normal and malignant prostate tissue and normal rectal wall …

Acute small bowel toxicity and preoperative chemoradiotherapy for rectal cancer: Investigating dose–volume relationships and role for inverse planning

LM Tho, M Glegg, J Paterson, C Yap… - International Journal of …, 2006 - Elsevier
Purpose: The relationship between volume of irradiated small bowel (VSB) and acute
toxicity in rectal cancer radiotherapy is poorly quantified, particularly in patients receiving …

Acid ceramidase upregulation in prostate cancer cells confers resistance to radiation: AC inhibition, a potential radiosensitizer

AEM Mahdy, JC Cheng, J Li, S Elojeimy… - Molecular Therapy, 2009 - cell.com
Radiation resistance in a subset of prostate tumors remains a challenge to prostate cancer
radiotherapy. The current study on the effects of radiation on prostate cancer cells reveals …

Acute toxicity of curative radiotherapy for intermediate-and high-risk localised prostate cancer in the EORTC trial 22991

O Matzinger, F Duclos, A Van den Bergh… - European journal of …, 2009 - Elsevier
INTRODUCTION: This trial randomly assessed short-term adjuvant hormonal therapy added
to radiotherapy (RT) for intermediate-and high-risk (UICC 1997 cT2a or cT1b-c with high …

Non-cancer mortality among people diagnosed with cancer (Australia)

PD Baade, L Fritschi, EG Eakin - Cancer Causes & Control, 2006 - Springer
Objective To investigate whether people diagnosed with cancer have an increased risk of
death from non-cancer causes compared to the general population. Methods The non …

Development of multiorgan finite element-based prostate deformation model enabling registration of endorectal coil magnetic resonance imaging for radiotherapy …

JM Hensel, C Ménard, PWM Chung… - International Journal of …, 2007 - Elsevier
Purpose: Endorectal coil (ERC) magnetic resonance imaging (MRI) provides superior
visualization of the prostate compared with computed tomography at the expense of …