Advances in Toxoplasma gondii Vaccines: Current Strategies and Challenges for Vaccine Development

KB Chu, FS Quan - Vaccines, 2021 - mdpi.com
Toxoplasmosis, caused by the apicomplexan parasite Toxoplasma gondii, is one of the most
damaging parasite-borne zoonotic diseases of global importance. While approximately one …

Advances in the development of anti-Toxoplasma gondii vaccines: challenges, opportunities, and perspectives

JL Wang, NZ Zhang, TT Li, JJ He, HM Elsheikha… - Trends in …, 2019 - cell.com
Important progress has been made in understanding how immunity is elicited against
Toxoplasma gondii–a complex pathogen with multiple mechanisms of immune evasion …

[图书][B] Parasitology: an integrated approach

A Gunn, SJ Pitt - 2022 - books.google.com
Parasitology Highly detailed textbook on parasites and parasite relationships The fully
revised edition of Parasitology: An Integrated Approach holds true to its engaging and easy …

Glycan arrays: from basic biochemical research to bioanalytical and biomedical applications

A Geissner, PH Seeberger - Annual Review of Analytical …, 2016 - annualreviews.org
A major branch of glycobiology and glycan-focused biomedicine studies the interaction
between carbohydrates and other biopolymers, most importantly, glycan-binding proteins …

Dismantling the bacterial glycocalyx: Chemical tools to probe, perturb, and image bacterial glycans

P Luong, DH Dube - Bioorganic & medicinal chemistry, 2021 - Elsevier
The bacterial glycocalyx is a quintessential drug target comprised of structurally distinct
glycans. Bacterial glycans bear unusual monosaccharide building blocks whose proper …

α-Gal-based vaccines: advances, opportunities, and perspectives

A Hodžić, L Mateos-Hernández, J de La Fuente… - Trends in …, 2020 - cell.com
Humans and crown catarrhines evolved with the inability to synthesize the oligosaccharide
galactose-α-1, 3-galactose (α-Gal). In turn, they naturally produce high quantities of the …

Moving towards improved vaccines for Toxoplasma gondii

Y Li, H Zhou - Expert opinion on biological therapy, 2018 - Taylor & Francis
Introduction: Toxoplasma gondii is an intracellular parasitic protozoan that infects almost all
warm-blooded animals and humans, resulting in threats to public health and economic …

Immunization with a novel mRNA vaccine, TGGT1_216200 mRNA-LNP, prolongs survival time in BALB/c mice against acute toxoplasmosis

Y Zhang, D Li, Y Shen, S Li, S Lu, B Zheng - Frontiers in Immunology, 2023 - frontiersin.org
Toxoplasma gondii, a specialized intracellular parasite, causes a widespread zoonotic
disease and is a severe threat to social and economic development. There is a lack of …

Anti-glycan antibodies: roles in human disease

JS Temme, DL Butler, JC Gildersleeve - Biochemical Journal, 2021 - portlandpress.com
Carbohydrate-binding antibodies play diverse and critical roles in human health.
Endogenous carbohydrate-binding antibodies that recognize bacterial, fungal, and other …

Immune system roles in pathogenesis, prognosis, control, and treatment of Toxoplasma gondii infection

MM Jafari, ZA Tabrizi, MS Dayer… - International …, 2023 - Elsevier
Toxoplasma gondii is the protozoan causative agent of toxoplasmosis in humans and warm-
blooded animals. Recent studies have illustrated that the immune system plays a pivotal role …